TY - JOUR

T1 - Influence of Lithium Salt on Escherichia coli Growth and Viability

AU - Chernova, Anna

AU - Pukhniarskaia, Daria

AU - Biryukov, Micheil

AU - Plotnikov, Evgenii

N1 - Funding Information: This article was funded by the Competitiveness Improvement Program TPU. Funding Information: This research was supported by Tomsk Polytechnic University development program. Publisher Copyright: © 2022 Mary Ann Liebert, Inc., publishers.

PY - 2022/2/1

Y1 - 2022/2/1

N2 - One of the promising current directions in biotechnology is the development of new microbiology cytoprotectors, which protect microorganisms against stressful environment conditions that finally allow maximizing yield of a target product. In this work, for the first time, the biological effect of organic lithium salts on Escherichia coli has been investigated and their use as promising agents for biotechnology is proposed. Research into the biological activity of inorganic lithium salts on prokaryotic cells has indicated that lithium cations may have a wide range of different effects, making them a promising nutrient supplement for biotechnology. However, there has been little research into the effects of organic lithium salts with antioxidant properties on microorganisms. Our pilot studies showed a protective effect on bacteria E. coli of some lithium salts in depleted environment. We revealed a stimulating effect on bacterial growth of lithium pyruvate and lithium succinate during cultivation of bacteria in different media.

AB - One of the promising current directions in biotechnology is the development of new microbiology cytoprotectors, which protect microorganisms against stressful environment conditions that finally allow maximizing yield of a target product. In this work, for the first time, the biological effect of organic lithium salts on Escherichia coli has been investigated and their use as promising agents for biotechnology is proposed. Research into the biological activity of inorganic lithium salts on prokaryotic cells has indicated that lithium cations may have a wide range of different effects, making them a promising nutrient supplement for biotechnology. However, there has been little research into the effects of organic lithium salts with antioxidant properties on microorganisms. Our pilot studies showed a protective effect on bacteria E. coli of some lithium salts in depleted environment. We revealed a stimulating effect on bacterial growth of lithium pyruvate and lithium succinate during cultivation of bacteria in different media.

KW - biological activity

KW - cytoprotector

KW - italic toggle="yes">E. coli

KW - Lithium salts

UR - http://www.scopus.com/inward/record.url?scp=85125052858&partnerID=8YFLogxK

U2 - 10.1089/ind.2021.0006

DO - 10.1089/ind.2021.0006

M3 - Article

AN - SCOPUS:85125052858

VL - 18

SP - 32

EP - 37

JO - Industrial Biotechnology

JF - Industrial Biotechnology

SN - 1550-9087

IS - 1

ER -