Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Influence of Internal and External Factors on the Production of Cytokines by Peripheral Blood Cells in Breast Cancer. / Autenshlyus, A. I.; Davletova, K. I.; Mikhaylova, E. S. и др.
в: Doklady Biochemistry and Biophysics, Том 493, № 1, 01.07.2020, стр. 178-180.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Influence of Internal and External Factors on the Production of Cytokines by Peripheral Blood Cells in Breast Cancer
AU - Autenshlyus, A. I.
AU - Davletova, K. I.
AU - Mikhaylova, E. S.
AU - Proskura, A. V.
AU - Varaksin, N. A.
AU - Bogachuk, A. P.
AU - Sidorov, S. V.
AU - Lyakhovich, V. V.
AU - Lipkin, V. M.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - The article focuses on the influence of human leukemia differentiation factor (HLDF), carcinoembryonic antigen (CEA), and polyclonal activators (PA) on cytokine production by peripheral blood cells in breast cancer and benign breast diseases. It was found that the influence of internal factors on the production of cytokines by the peripheral blood cells is associated with lymphatic metastasis (CEA: IL-10; HLDF: IL-6, IL-1β, TNF-α, and G-CSF). One special circumstance was that there were no differences between the production of cytokines by peripheral blood cells in the patients with breast cancer compared to the patients with benign breast diseases with a high risk of malignant transformation. This is evidence of the functional similarity of peripheral blood cells in patients with these conditions. Cytokine production under the influence of PA was different only in case of TNF-α in all study groups.
AB - The article focuses on the influence of human leukemia differentiation factor (HLDF), carcinoembryonic antigen (CEA), and polyclonal activators (PA) on cytokine production by peripheral blood cells in breast cancer and benign breast diseases. It was found that the influence of internal factors on the production of cytokines by the peripheral blood cells is associated with lymphatic metastasis (CEA: IL-10; HLDF: IL-6, IL-1β, TNF-α, and G-CSF). One special circumstance was that there were no differences between the production of cytokines by peripheral blood cells in the patients with breast cancer compared to the patients with benign breast diseases with a high risk of malignant transformation. This is evidence of the functional similarity of peripheral blood cells in patients with these conditions. Cytokine production under the influence of PA was different only in case of TNF-α in all study groups.
KW - breast cancer
KW - carcinoembryonic antigen
KW - cytokines
KW - HLDF
KW - polyclonal activators
KW - DISEASE
UR - http://www.scopus.com/inward/record.url?scp=85090337457&partnerID=8YFLogxK
U2 - 10.1134/S1607672920040031
DO - 10.1134/S1607672920040031
M3 - Article
C2 - 32894459
AN - SCOPUS:85090337457
VL - 493
SP - 178
EP - 180
JO - Doklady Biochemistry and Biophysics
JF - Doklady Biochemistry and Biophysics
SN - 1607-6729
IS - 1
ER -
ID: 25298230