Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Induced pluripotent stem cell line, IMGTi003-A, derived from skin fibroblasts of an intellectually disabled patient with ring chromosome 13. / Nikitina, T. V.; Menzorov, A. G.; Kashevarova, A. A. и др.
в: Stem Cell Research, Том 33, 01.12.2018, стр. 260-264.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Induced pluripotent stem cell line, IMGTi003-A, derived from skin fibroblasts of an intellectually disabled patient with ring chromosome 13
AU - Nikitina, T. V.
AU - Menzorov, A. G.
AU - Kashevarova, A. A.
AU - Gridina, M. M.
AU - Khabarova, A. A.
AU - Yakovleva, Yu S.
AU - Lopatkina, M. E.
AU - Pristyazhnyuk, I. E.
AU - Vasilyev, S. A.
AU - Serov, O. L.
AU - Lebedev, I. N.
N1 - Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Skin fibroblasts from a patient with neurodevelopmental and speech delay, anxiety disorder, macrocephaly, microorchidism, multiple anomalies of internal organs and ring chromosome 13 were reprogrammed into induced pluripotent stem cells (iPSCs) to generate a clonal stem cell line IMGTi003-A (iTAF6-6). IMGTi003-A pluripotency was demonstrated by three germ layer differentiation capacity in vitro, and this cell line had a mosaic karyotype with 46,XY,r(13) as a predominant cell subpopulation. IMGTi003-A line is a good model for studying of the mitotic instability of the ring chromosome 13.
AB - Skin fibroblasts from a patient with neurodevelopmental and speech delay, anxiety disorder, macrocephaly, microorchidism, multiple anomalies of internal organs and ring chromosome 13 were reprogrammed into induced pluripotent stem cells (iPSCs) to generate a clonal stem cell line IMGTi003-A (iTAF6-6). IMGTi003-A pluripotency was demonstrated by three germ layer differentiation capacity in vitro, and this cell line had a mosaic karyotype with 46,XY,r(13) as a predominant cell subpopulation. IMGTi003-A line is a good model for studying of the mitotic instability of the ring chromosome 13.
KW - CULTURES
KW - Skin/metabolism
KW - Fibroblasts/metabolism
KW - Humans
KW - Chromosomes, Human, Pair 13
KW - Induced Pluripotent Stem Cells/metabolism
KW - Male
KW - Mentally Disabled Persons
KW - Aged
KW - Ring Chromosomes
UR - http://www.scopus.com/inward/record.url?scp=85057271477&partnerID=8YFLogxK
U2 - 10.1016/j.scr.2018.11.009
DO - 10.1016/j.scr.2018.11.009
M3 - Article
C2 - 30500678
AN - SCOPUS:85057271477
VL - 33
SP - 260
EP - 264
JO - Stem Cell Research
JF - Stem Cell Research
SN - 1873-5061
ER -
ID: 17554774