Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension

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Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension. / Abramova, T. O.; Ryazanova, M. A.; Antonov, E. V. и др.

в: Molecular Biology, Том 51, № 3, 01.05.2017, стр. 389-392.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Author

Abramova, T. O. ; Ryazanova, M. A. ; Antonov, E. V. и др. / Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension. в: Molecular Biology. 2017 ; Том 51, № 3. стр. 389-392.

BibTeX

@article{6080da85a7e24340946f6b24348c92de,

title = "Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension",

abstract = "The concentration of soluble epoxide hydrolase (sEH) protein was studied in renal medulla of adult rats from hypertensive ISIAH strain and normotensive WAG strain. The sEH is a key enzyme in metabolism of epoxyeicosatrienoic acids capable of activating endothelial NO-synthase and nitrogen oxide formation, and therefore being vasodilators. An increase in the sEH protein concentration (that we found) allows one to assume that the oxidative stress is increased in the renal medulla of hypertensive rats, and the bloodflow is decreased.",

keywords = "arterial hypertension, ELISA, ISIAH rat strain, real time PCR, renal medulla, soluble epoxide hydrolase",

author = "Abramova, {T. O.} and Ryazanova, {M. A.} and Antonov, {E. V.} and Redina, {O. E.} and Markel, {A. L.}",

year = "2017",

month = may,

day = "1",

doi = "10.1134/S0026893317020029",

language = "English",

volume = "51",

pages = "389--392",

journal = "Molecular Biology",

issn = "0026-8933",

publisher = "Maik Nauka-Interperiodica Publishing",

number = "3",

}

RIS

TY - JOUR

T1 - Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension

AU - Abramova, T. O.

AU - Ryazanova, M. A.

AU - Antonov, E. V.

AU - Redina, O. E.

AU - Markel, A. L.

PY - 2017/5/1

Y1 - 2017/5/1

N2 - The concentration of soluble epoxide hydrolase (sEH) protein was studied in renal medulla of adult rats from hypertensive ISIAH strain and normotensive WAG strain. The sEH is a key enzyme in metabolism of epoxyeicosatrienoic acids capable of activating endothelial NO-synthase and nitrogen oxide formation, and therefore being vasodilators. An increase in the sEH protein concentration (that we found) allows one to assume that the oxidative stress is increased in the renal medulla of hypertensive rats, and the bloodflow is decreased.

AB - The concentration of soluble epoxide hydrolase (sEH) protein was studied in renal medulla of adult rats from hypertensive ISIAH strain and normotensive WAG strain. The sEH is a key enzyme in metabolism of epoxyeicosatrienoic acids capable of activating endothelial NO-synthase and nitrogen oxide formation, and therefore being vasodilators. An increase in the sEH protein concentration (that we found) allows one to assume that the oxidative stress is increased in the renal medulla of hypertensive rats, and the bloodflow is decreased.

KW - arterial hypertension

KW - ELISA

KW - ISIAH rat strain

KW - real time PCR

KW - renal medulla

KW - soluble epoxide hydrolase

UR - http://www.scopus.com/inward/record.url?scp=85021289281&partnerID=8YFLogxK

U2 - 10.1134/S0026893317020029

DO - 10.1134/S0026893317020029

M3 - Article

AN - SCOPUS:85021289281

VL - 51

SP - 389

EP - 392

JO - Molecular Biology

JF - Molecular Biology

SN - 0026-8933

IS - 3

ER -

ID: 8674927