TY - JOUR

T1 - Inactivation and Degradation of Influenza A Virus on the Surface of Photoactive Self-Cleaning Cotton Fabric Functionalized with Nanocrystalline TiO2

AU - Selishchev, Dmitry

AU - Stepanov, Grigory

AU - Sergeeva, Mariia

AU - Solovyeva, Maria

AU - Zhuravlev, Evgenii

AU - Komissarov, Andrey

AU - Richter, Vladimir

AU - Kozlov, Denis

N1 - Funding Information: The study was supported by the grant for the implementation of the strategic academic leadership program “Priority 2030” in Novosibirsk State University. The experiments on virus inactivation in Smorodintsev Research Institute of Influenza were supported by the Russian Foundation for Basic Research according to research project No. 18-29-17055. Publisher Copyright: © 2022 by the authors.

PY - 2022/11

Y1 - 2022/11

N2 - Chemical modification of cotton-rich fabrics with TiO2 nanoparticles results in photoactive self-cleaning textiles, which can provide, under UV or solar radiation, complete oxidation of low-molecular compounds, degradation of supramolecular structures, and inactivation of microorganisms due to the photocatalytic effect. In this paper, we describe, based on the example of influenza A (H1N1) virus, a photoinduced antiviral effect of cotton fabric functionalized with nanocrystalline TiO2. Fast inactivation of influenza virus occurs on the irradiated surface of photoactive fabric due to adsorption and photocatalytic degradation. The TiO2 component in the prepared fabric increases the adsorption effect compared to initial cotton due to a high specific area of TiO2 nanocrystallites. Long-term irradiation leads to destruction of all virion structures to the point of RNA molecules. In contrast to pristine cotton, no virus RNA is detected using the polymerase chain reaction (PCR) technique after long-term irradiation of photoactive fabric. The results of this study underline the potential of photoactive self-cleaning fabrics for application in air purification systems and personal protective clothes to provide permanent protection of people against harmful chemical and biological pollutants.

AB - Chemical modification of cotton-rich fabrics with TiO2 nanoparticles results in photoactive self-cleaning textiles, which can provide, under UV or solar radiation, complete oxidation of low-molecular compounds, degradation of supramolecular structures, and inactivation of microorganisms due to the photocatalytic effect. In this paper, we describe, based on the example of influenza A (H1N1) virus, a photoinduced antiviral effect of cotton fabric functionalized with nanocrystalline TiO2. Fast inactivation of influenza virus occurs on the irradiated surface of photoactive fabric due to adsorption and photocatalytic degradation. The TiO2 component in the prepared fabric increases the adsorption effect compared to initial cotton due to a high specific area of TiO2 nanocrystallites. Long-term irradiation leads to destruction of all virion structures to the point of RNA molecules. In contrast to pristine cotton, no virus RNA is detected using the polymerase chain reaction (PCR) technique after long-term irradiation of photoactive fabric. The results of this study underline the potential of photoactive self-cleaning fabrics for application in air purification systems and personal protective clothes to provide permanent protection of people against harmful chemical and biological pollutants.

KW - antiviral properties

KW - influenza virus

KW - photoactive cotton

KW - RNA degradation

KW - self-cleaning textile

KW - TiO photocatalyst

KW - TiO2 photocatalyst

UR - http://www.scopus.com/inward/record.url?scp=85141799824&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/64d9d42e-0be9-31d3-bc22-e49eabd9ca2d/

U2 - 10.3390/catal12111298

DO - 10.3390/catal12111298

M3 - Article

AN - SCOPUS:85141799824

VL - 12

JO - Catalysts

JF - Catalysts

SN - 2073-4344

IS - 11

M1 - 1298

ER -