Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
In vitro photodynamic inactivation of mycobacterium tuberculosis by radahlorin. / Bredikhin, D. A.; Nikonov, S. D.; Cherednichenko, A. G. и др.
в: Tuberculosis and Lung Diseases, Том 96, № 1, 01.01.2018, стр. 5-10.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - In vitro photodynamic inactivation of mycobacterium tuberculosis by radahlorin
AU - Bredikhin, D. A.
AU - Nikonov, S. D.
AU - Cherednichenko, A. G.
AU - Petrenko, T. I.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Goal to detect the best mode of in vitro photodynamic inactivation of M. tuberculosis by Radahlorin.Subjects and methods. The activity of culture of M. tuberculosis, H37Rv strain, photosensitized by 0.00005% Radohlorin was compared and the intensity of growth was assessed after photodynamic inactivation by different doses of light energy with 662 nm wavelength. Results. For the first time, anti-microbial properties of E6 chlorine in the form of medicamental photosensitizer (0.00005% Radohlorin) suppressing museum strain of M. tuberculosis of H37Rv were detected. Photoinactivation of M. tuberculosis depends on the dose and achieves its maximum in 10 minutes of light exposure with light energy of 0.5 W.
AB - Goal to detect the best mode of in vitro photodynamic inactivation of M. tuberculosis by Radahlorin.Subjects and methods. The activity of culture of M. tuberculosis, H37Rv strain, photosensitized by 0.00005% Radohlorin was compared and the intensity of growth was assessed after photodynamic inactivation by different doses of light energy with 662 nm wavelength. Results. For the first time, anti-microbial properties of E6 chlorine in the form of medicamental photosensitizer (0.00005% Radohlorin) suppressing museum strain of M. tuberculosis of H37Rv were detected. Photoinactivation of M. tuberculosis depends on the dose and achieves its maximum in 10 minutes of light exposure with light energy of 0.5 W.
KW - Anti-bacterial therapy
KW - Anti-microbial photodynamic therapy
KW - Chemotherapy of tuberculosis
KW - M. tuberculosis H37Rv
KW - Photodynamic inactivation of bacteria
KW - Photosensitizers
KW - Radahlorin
UR - http://www.scopus.com/inward/record.url?scp=85043765948&partnerID=8YFLogxK
U2 - 10.21292/2075-1230-2018-96-1-5-10
DO - 10.21292/2075-1230-2018-96-1-5-10
M3 - Article
AN - SCOPUS:85043765948
VL - 96
SP - 5
EP - 10
JO - Tuberculosis and Lung Diseases
JF - Tuberculosis and Lung Diseases
SN - 2075-1230
IS - 1
ER -
ID: 12100710