Результаты исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › Рецензирование
In silico modeling gas molecules transfer through the biomembrane by kinks-solitons. / Mokrushnikov, P. V.; Lezhnev, E. V.; Rudyak, V. Ya.
International Conference on the Methods of Aerophysical Research, ICMAR 2020. ред. / Vasily M. Fomin; Alexander Shiplyuk. American Institute of Physics Inc., 2021. 040054 (AIP Conference Proceedings; Том 2351).Результаты исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › Рецензирование
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TY - GEN
T1 - In silico modeling gas molecules transfer through the biomembrane by kinks-solitons
AU - Mokrushnikov, P. V.
AU - Lezhnev, E. V.
AU - Rudyak, V. Ya
N1 - Funding Information: This work was partially supported by the Russian Foundation for Basic Research (Grant No. 19-01-00399). Publisher Copyright: © 2021 Author(s). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/5/24
Y1 - 2021/5/24
N2 - It is shown that the mechanism of the gas molecules transfer through the lipid bilayer can be connected with the kink-solitons. They are appeared in the lipid bilayer as a result of structural changes in biomembranes. The analytical model describing the behavior of kink-solitons in the finite hydrocarbon chain is presented. The kink-solitons are formed during the folding of the erythrocyte as it moves along the microcapillaries. The equation of the kink-soliton motion is derived. This equation is numerically solved. It is shown that kink-solitons can appear in both saturated and unsaturated alkyl chains. In unsaturated chains, the soliton is "smeared out,"CH2-groups vibrate around C=C bonds with a significant amplitude, taking away part of the soliton's energy. The transport of gas molecules by kink-solitons in unsaturated chains is hindered in comparison with saturated hydrocarbon chains. When the mechanical stress field changes, a sharp change in membrane permeability occurs.
AB - It is shown that the mechanism of the gas molecules transfer through the lipid bilayer can be connected with the kink-solitons. They are appeared in the lipid bilayer as a result of structural changes in biomembranes. The analytical model describing the behavior of kink-solitons in the finite hydrocarbon chain is presented. The kink-solitons are formed during the folding of the erythrocyte as it moves along the microcapillaries. The equation of the kink-soliton motion is derived. This equation is numerically solved. It is shown that kink-solitons can appear in both saturated and unsaturated alkyl chains. In unsaturated chains, the soliton is "smeared out,"CH2-groups vibrate around C=C bonds with a significant amplitude, taking away part of the soliton's energy. The transport of gas molecules by kink-solitons in unsaturated chains is hindered in comparison with saturated hydrocarbon chains. When the mechanical stress field changes, a sharp change in membrane permeability occurs.
UR - http://www.scopus.com/inward/record.url?scp=85107175307&partnerID=8YFLogxK
U2 - 10.1063/5.0053082
DO - 10.1063/5.0053082
M3 - Conference contribution
AN - SCOPUS:85107175307
T3 - AIP Conference Proceedings
BT - International Conference on the Methods of Aerophysical Research, ICMAR 2020
A2 - Fomin, Vasily M.
A2 - Shiplyuk, Alexander
PB - American Institute of Physics Inc.
T2 - 20th International Conference on the Methods of Aerophysical Research, ICMAR 2020
Y2 - 1 November 2020 through 7 November 2020
ER -
ID: 28866304