Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Humoral immunity to influenza in an at-risk population and severe influenza cases in Russia in 2016–2017. / Ilyicheva, Tatyana N.; Durymanov, Alexander G.; Svyatchenko, Svetlana V. и др.
в: Archives of Virology, Том 163, № 10, 01.10.2018, стр. 2675-2685.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Humoral immunity to influenza in an at-risk population and severe influenza cases in Russia in 2016–2017
AU - Ilyicheva, Tatyana N.
AU - Durymanov, Alexander G.
AU - Svyatchenko, Svetlana V.
AU - Marchenko, Vasily Yu
AU - Sobolev, Ivan A.
AU - Bakulina, Anastasiya Yu
AU - Goncharova, Natalia I.
AU - Kolosova, Natalia P.
AU - Susloparov, Ivan M.
AU - Pyankova, Olga G.
AU - Ryzhikov, Alexander B.
AU - Maksyutov, Rinat A.
N1 - Publisher Copyright: © 2018, Springer-Verlag GmbH Austria, part of Springer Nature.
PY - 2018/10/1
Y1 - 2018/10/1
N2 - This work aimed to analyze the herd immunity to influenza among a Russian population living in regions with an increased risk of emergence of viruses with pandemic potential, and to isolate and investigate virus strains from severe influenza cases, including fatal cases, during the 2016–2017 epidemic season. In November 2016 – March 2017 highly pathogenic influenza outbreaks were registered in Russia among wild birds and poultry. No cases of human infection were registered. Analysis of 760 sera from people who had contact with infected or perished birds revealed the presence of antibodies to A(H5N1) virus of clade 2.3.2.1c and A(H5N8) virus of clade 2.3.4.4. The 2016–2017 influenza epidemic season in Russia began in weeks 46–47 of 2016 with predominant circulation of influenza A(H3N2) viruses. Strains isolated from severe influenza cases mainly belonged to 3C.2a.2 and 3C.2a.3 genetic groups. Up to the 8th week of 2017 severe influenza cases were often caused by influenza B viruses which belonged to 1A genetic group with antigenic properties similar to B/Brisbane/60/2008. All influenza A and B virus strains isolated in the 2016–2017 epidemic season were sensitive to oseltamivir and zanamivir.
AB - This work aimed to analyze the herd immunity to influenza among a Russian population living in regions with an increased risk of emergence of viruses with pandemic potential, and to isolate and investigate virus strains from severe influenza cases, including fatal cases, during the 2016–2017 epidemic season. In November 2016 – March 2017 highly pathogenic influenza outbreaks were registered in Russia among wild birds and poultry. No cases of human infection were registered. Analysis of 760 sera from people who had contact with infected or perished birds revealed the presence of antibodies to A(H5N1) virus of clade 2.3.2.1c and A(H5N8) virus of clade 2.3.4.4. The 2016–2017 influenza epidemic season in Russia began in weeks 46–47 of 2016 with predominant circulation of influenza A(H3N2) viruses. Strains isolated from severe influenza cases mainly belonged to 3C.2a.2 and 3C.2a.3 genetic groups. Up to the 8th week of 2017 severe influenza cases were often caused by influenza B viruses which belonged to 1A genetic group with antigenic properties similar to B/Brisbane/60/2008. All influenza A and B virus strains isolated in the 2016–2017 epidemic season were sensitive to oseltamivir and zanamivir.
KW - VACCINE EFFECTIVENESS
KW - A(H3N2)
KW - SEASON
KW - VIRUS
UR - http://www.scopus.com/inward/record.url?scp=85048042974&partnerID=8YFLogxK
U2 - 10.1007/s00705-018-3904-9
DO - 10.1007/s00705-018-3904-9
M3 - Article
C2 - 29872951
AN - SCOPUS:85048042974
VL - 163
SP - 2675
EP - 2685
JO - Archives of Virology
JF - Archives of Virology
SN - 0304-8608
IS - 10
ER -
ID: 13755507