Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
High-resolution MRI data of the brain of C57BL/6J and BTBR mice in three anatomical views. / Ryabushkina, Yulia A.; Shevelev, Oleg B.; Kisaretova, Polina E. и др.
в: Data in Brief, Том 39, 107619, 12.2021.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - High-resolution MRI data of the brain of C57BL/6J and BTBR mice in three anatomical views
AU - Ryabushkina, Yulia A.
AU - Shevelev, Oleg B.
AU - Kisaretova, Polina E.
AU - Sozonov, Nikita G.
AU - Ayriyants, Kseniya A.
AU - Bondar, Natalya P.
AU - Reshetnikov, Vasiliy V.
N1 - Funding Information: This study was supported by the Russian Science Foundation (grant # 21-15-00142) and by State Budget Projects (Russia) # 0259-2021-0013. The English language was corrected and certified by shevchuk-editing.com. Publisher Copyright: © 2021
PY - 2021/12
Y1 - 2021/12
N2 - The research on strain-, sex-, and stress-specific differences in structural and functional connectivity of the brain is important for elucidating various behavioral features and etiologies of psychiatric disorders. Socially impaired BTBR mice are considered a model of autism spectrum disorders. Here we present high-resolution magnetic resonance imaging data from the brain of 89 adolescent mice (C57BL/6J and BTBR) in axial, sagittal, and coronal views. The study [1] includes both females and males differed in early-life experience (normally reared or subjected to prolonged maternal separation: 3 h daily from postnatal day 2 to 15). The MRI data were obtained on a horizontal tomograph Biospec 117/16 instrument with a magnetic field strength of 11.7 T. Thus, multislice Turbo RARE T2-weighted images of the brain were captured in eight groups of mice. Altogether, these data allow to evaluate strain-, sex-, and stress-specific alterations in the volumes of various brain structures and to better understand the relation between brain structural differences and behavioral abnormalities.
AB - The research on strain-, sex-, and stress-specific differences in structural and functional connectivity of the brain is important for elucidating various behavioral features and etiologies of psychiatric disorders. Socially impaired BTBR mice are considered a model of autism spectrum disorders. Here we present high-resolution magnetic resonance imaging data from the brain of 89 adolescent mice (C57BL/6J and BTBR) in axial, sagittal, and coronal views. The study [1] includes both females and males differed in early-life experience (normally reared or subjected to prolonged maternal separation: 3 h daily from postnatal day 2 to 15). The MRI data were obtained on a horizontal tomograph Biospec 117/16 instrument with a magnetic field strength of 11.7 T. Thus, multislice Turbo RARE T2-weighted images of the brain were captured in eight groups of mice. Altogether, these data allow to evaluate strain-, sex-, and stress-specific alterations in the volumes of various brain structures and to better understand the relation between brain structural differences and behavioral abnormalities.
KW - Brain anatomy
KW - BTBR
KW - C57BL/6J
KW - Early-life stress
KW - MRI
KW - Sex-specific
KW - Strain-specific
UR - http://www.scopus.com/inward/record.url?scp=85119596239&partnerID=8YFLogxK
U2 - 10.1016/j.dib.2021.107619
DO - 10.1016/j.dib.2021.107619
M3 - Article
C2 - 34877386
AN - SCOPUS:85119596239
VL - 39
JO - Data in Brief
JF - Data in Brief
SN - 2352-3409
M1 - 107619
ER -
ID: 34744663