TY - JOUR

T1 - Genetic Organization of Open Chromatin Domains Situated in Polytene Chromosome Interbands in Drosophila

AU - Zykova, T. Yu

AU - Popova, O. O.

AU - Khoroshko, V. A.

AU - Levitsky, V. G.

AU - Lavrov, S. A.

AU - Zhimulev, I. F.

PY - 2018/11/1

Y1 - 2018/11/1

N2 - New data on the organization of genes entirely located in the open domains for chromatin transcription and occupying only one chromosome structure (interband) were obtained. The characteristic features of these genes are the small size (on average, 1–2 kb), depletion of the replicative complex proteins in the regulatory region, and the presence of specific motifs for binding transcription factors, as compared to the genes occupying two structures (interband and gray band). The biological function of these genes is associated primarily with the processes of gene expression and RNA metabolism.

AB - New data on the organization of genes entirely located in the open domains for chromatin transcription and occupying only one chromosome structure (interband) were obtained. The characteristic features of these genes are the small size (on average, 1–2 kb), depletion of the replicative complex proteins in the regulatory region, and the presence of specific motifs for binding transcription factors, as compared to the genes occupying two structures (interband and gray band). The biological function of these genes is associated primarily with the processes of gene expression and RNA metabolism.

UR - http://www.scopus.com/inward/record.url?scp=85059502048&partnerID=8YFLogxK

U2 - 10.1134/S1607672918060078

DO - 10.1134/S1607672918060078

M3 - Article

C2 - 30607724

AN - SCOPUS:85059502048

VL - 483

SP - 297

EP - 301

JO - Doklady Biochemistry and Biophysics

JF - Doklady Biochemistry and Biophysics

SN - 1607-6729

IS - 1

ER -