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Generation of two iPSC lines (ICGi008-A and ICGi008-B) from skin fibroblasts of a patient with early-onset Alzheimer's disease caused by London familial APP mutation (V717I). / Grigor'eva, E. V.; Malankhanova, T. B.; Ustyantseva, E. I. и др.

в: Stem Cell Research, Том 36, 101415, 01.04.2019.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

Harvard

Grigor'eva, EV, Malankhanova, TB, Ustyantseva, EI, Minina, JM, Redina, OE, Morozov, VV, Shevela, AI, Zakian, SM & Medvedev, SP 2019, 'Generation of two iPSC lines (ICGi008-A and ICGi008-B) from skin fibroblasts of a patient with early-onset Alzheimer's disease caused by London familial APP mutation (V717I)', Stem Cell Research, Том. 36, 101415. https://doi.org/10.1016/j.scr.2019.101415

APA

Grigor'eva, E. V., Malankhanova, T. B., Ustyantseva, E. I., Minina, J. M., Redina, O. E., Morozov, V. V., Shevela, A. I., Zakian, S. M., & Medvedev, S. P. (2019). Generation of two iPSC lines (ICGi008-A and ICGi008-B) from skin fibroblasts of a patient with early-onset Alzheimer's disease caused by London familial APP mutation (V717I). Stem Cell Research, 36, [101415]. https://doi.org/10.1016/j.scr.2019.101415

Vancouver

Grigor'eva EV, Malankhanova TB, Ustyantseva EI, Minina JM, Redina OE, Morozov VV и др. Generation of two iPSC lines (ICGi008-A and ICGi008-B) from skin fibroblasts of a patient with early-onset Alzheimer's disease caused by London familial APP mutation (V717I). Stem Cell Research. 2019 апр. 1;36:101415. doi: 10.1016/j.scr.2019.101415

Author

BibTeX

@article{46f576685e8244fab9a225629b3944a8,
title = "Generation of two iPSC lines (ICGi008-A and ICGi008-B) from skin fibroblasts of a patient with early-onset Alzheimer's disease caused by London familial APP mutation (V717I)",
abstract = "The induced pluripotent stem cell (iPSC) lines ICGi008-A and ICGi008-B were generated from dermal fibroblasts using episomal vectors expressing pluripotency factors. Dermal fibroblasts were obtained from a 55 year old male Сaucasian familial Alzheimer's disease (AD) patient carrying heterozygous V717I mutation in the APP gene. The generated iPSC lines maintained the original APP genotype, expressed pluripotency markers, exhibited a normal karyotype and retained the ability to differentiate into cell types of the three germ layers. The iPSC lines will be useful for the study of the AD molecular and cellular mechanisms and drug screening.",
author = "Grigor'eva, {E. V.} and Malankhanova, {T. B.} and Ustyantseva, {E. I.} and Minina, {J. M.} and Redina, {O. E.} and Morozov, {V. V.} and Shevela, {A. I.} and Zakian, {S. M.} and Medvedev, {S. P.}",
note = "Copyright {\textcopyright} 2019 The Authors. Published by Elsevier B.V. All rights reserved.",
year = "2019",
month = apr,
day = "1",
doi = "10.1016/j.scr.2019.101415",
language = "English",
volume = "36",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Generation of two iPSC lines (ICGi008-A and ICGi008-B) from skin fibroblasts of a patient with early-onset Alzheimer's disease caused by London familial APP mutation (V717I)

AU - Grigor'eva, E. V.

AU - Malankhanova, T. B.

AU - Ustyantseva, E. I.

AU - Minina, J. M.

AU - Redina, O. E.

AU - Morozov, V. V.

AU - Shevela, A. I.

AU - Zakian, S. M.

AU - Medvedev, S. P.

N1 - Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.

PY - 2019/4/1

Y1 - 2019/4/1

N2 - The induced pluripotent stem cell (iPSC) lines ICGi008-A and ICGi008-B were generated from dermal fibroblasts using episomal vectors expressing pluripotency factors. Dermal fibroblasts were obtained from a 55 year old male Сaucasian familial Alzheimer's disease (AD) patient carrying heterozygous V717I mutation in the APP gene. The generated iPSC lines maintained the original APP genotype, expressed pluripotency markers, exhibited a normal karyotype and retained the ability to differentiate into cell types of the three germ layers. The iPSC lines will be useful for the study of the AD molecular and cellular mechanisms and drug screening.

AB - The induced pluripotent stem cell (iPSC) lines ICGi008-A and ICGi008-B were generated from dermal fibroblasts using episomal vectors expressing pluripotency factors. Dermal fibroblasts were obtained from a 55 year old male Сaucasian familial Alzheimer's disease (AD) patient carrying heterozygous V717I mutation in the APP gene. The generated iPSC lines maintained the original APP genotype, expressed pluripotency markers, exhibited a normal karyotype and retained the ability to differentiate into cell types of the three germ layers. The iPSC lines will be useful for the study of the AD molecular and cellular mechanisms and drug screening.

UR - http://www.scopus.com/inward/record.url?scp=85062390628&partnerID=8YFLogxK

U2 - 10.1016/j.scr.2019.101415

DO - 10.1016/j.scr.2019.101415

M3 - Article

C2 - 30851551

AN - SCOPUS:85062390628

VL - 36

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

M1 - 101415

ER -

ID: 18678460