Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Full-Term In Vivo Development of Frozen–Thawed Mammalian Diapausing Embryos. / Amstislavsky, Sergei; Rozhkova, Irina; Rakhmanova, Tamara и др.
в: Reproduction in Domestic Animals, Том 60, № 9, e70123, 2025.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Full-Term In Vivo Development of Frozen–Thawed Mammalian Diapausing Embryos
AU - Amstislavsky, Sergei
AU - Rozhkova, Irina
AU - Rakhmanova, Tamara
AU - Kozeneva, Varvara
AU - Brusentsev, Eugeny
N1 - Funding: This study was supported by Russian Science Foundation (project no. 23-24-00313). Animal maintenance supported by budget Project of ICG SB RAS (FWNR-2022-0023).
PY - 2025
Y1 - 2025
N2 - Embryonic diapause is widespread among mammals. This is the first report of successful post-thaw in vivo development of mammalian embryos cryopreserved at the diapause stage using mouse as a model species. Live offspring were obtained after cryopreservation of murine embryos and their transfer to pseudo-pregnant recipients. The sex ratio at birth was male-skewed, and the offspring were fertile. The results may open new possibilities for applying the Genome Resource Banking concept to diapausing mammalian species.
AB - Embryonic diapause is widespread among mammals. This is the first report of successful post-thaw in vivo development of mammalian embryos cryopreserved at the diapause stage using mouse as a model species. Live offspring were obtained after cryopreservation of murine embryos and their transfer to pseudo-pregnant recipients. The sex ratio at birth was male-skewed, and the offspring were fertile. The results may open new possibilities for applying the Genome Resource Banking concept to diapausing mammalian species.
KW - cryopreservation
KW - diapause
KW - embryo transfer
KW - mice
KW - offspring
UR - https://www.mendeley.com/catalogue/a723e5c5-d050-3cd1-a45c-5305c38c2a56/
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105015083938&origin=inward
U2 - 10.1111/rda.70123
DO - 10.1111/rda.70123
M3 - Article
VL - 60
JO - Reproduction in Domestic Animals
JF - Reproduction in Domestic Animals
SN - 0936-6768
IS - 9
M1 - e70123
ER -
ID: 69361743