TY - JOUR

T1 - Exploration of Antibacterial Activity of Plant-Mediated Green Synthesis of Cadmium Sulfide Nanoparticles

AU - Khan Mohmand, Numan Zada

AU - Ullah, Habib

AU - Shah, Yasir

AU - Ahmad, Saeed

AU - Hassan, Amir

AU - Ali, Liaqat

AU - Rahman, Hanif Ur

PY - 2024

Y1 - 2024

N2 - Today, cadmium sulfide nanoparticles are extensively used in various fields, including medical sciences, engineering, drug delivery, photovoltaic cells, bio-imaging techniques, molecular pathology, and bio-sensing. This study uses a green, eco-friendly approach to explore biosynthesized CdS NPs characterization and their antibacterial activity. A uniform color change from light yellow to greenish yellow indicated the formation of cadmium sulfide nanoparticles, further confirmed by a blue shift at 450 nm in optical absorption spectra. The XRD (X-ray diffraction) analysis confirmed the crystallinity of elements present in nanoparticles, while the coating of Coronopus didymus phytochemicals around the nanoparticle surface was confirmed by Fourier transform infrared (FT-IR) analysis. Next, SEM analysis was performed to investigate the morphology and size of the CdS nanoparticles. The antibacterial activity of the synthesized CdS nanoparticles was evaluated against gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae) and gram-positive bacteria (Staphylococcus aureus); their result shows the highest zone of inhibition at a medium concentration of 40 mg/ml in Klebsiella pneumoniae (27.5±0.70), Escherichia coli (21.5±0.70), and Staphylococcus aureus (12.15±0.25). Our approach presents a successful, green, and cost-efficient method for synthesizing CdS nanoparticles and exploring their antibacterial activity.

AB - Today, cadmium sulfide nanoparticles are extensively used in various fields, including medical sciences, engineering, drug delivery, photovoltaic cells, bio-imaging techniques, molecular pathology, and bio-sensing. This study uses a green, eco-friendly approach to explore biosynthesized CdS NPs characterization and their antibacterial activity. A uniform color change from light yellow to greenish yellow indicated the formation of cadmium sulfide nanoparticles, further confirmed by a blue shift at 450 nm in optical absorption spectra. The XRD (X-ray diffraction) analysis confirmed the crystallinity of elements present in nanoparticles, while the coating of Coronopus didymus phytochemicals around the nanoparticle surface was confirmed by Fourier transform infrared (FT-IR) analysis. Next, SEM analysis was performed to investigate the morphology and size of the CdS nanoparticles. The antibacterial activity of the synthesized CdS nanoparticles was evaluated against gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae) and gram-positive bacteria (Staphylococcus aureus); their result shows the highest zone of inhibition at a medium concentration of 40 mg/ml in Klebsiella pneumoniae (27.5±0.70), Escherichia coli (21.5±0.70), and Staphylococcus aureus (12.15±0.25). Our approach presents a successful, green, and cost-efficient method for synthesizing CdS nanoparticles and exploring their antibacterial activity.

KW - Antibacterial activity

KW - Coronopus didymus

KW - cadmium sulfide (CdS) nanoparticles

KW - extraction

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85204687886&origin=inward&txGid=b7587257f8a7b6b3d2f56c04b2733736

UR - https://www.mendeley.com/catalogue/b56c501b-9431-3c66-b9cf-c4fa7612b0b0/

U2 - 10.33263/LIANBS132.074

DO - 10.33263/LIANBS132.074

M3 - Article

VL - 13

JO - Letters in Applied NanoBioScience

JF - Letters in Applied NanoBioScience

SN - 2284-6808

IS - 2

M1 - 74

ER -