Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Experience in Continuous Neurobiocontrol Using fMRI Signals from the Primary Motor Cortex Using a 1.5-T MR Tomograph. / Mel’nikov, M. E.; Savelov, A. A.; Shtark, M. B. и др.
в: Neuroscience and Behavioral Physiology, Том 48, № 4, 01.05.2018, стр. 474-482.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Experience in Continuous Neurobiocontrol Using fMRI Signals from the Primary Motor Cortex Using a 1.5-T MR Tomograph
AU - Mel’nikov, M. E.
AU - Savelov, A. A.
AU - Shtark, M. B.
AU - Pokrovskii, M. A.
AU - Petrovskii, E. D.
AU - Kozlova, L. I.
AU - Mazhirina, K. G.
AU - Bezmaternykh, D. D.
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Biocontrol based on fMRI signals from the motor area of the cortex is a potential approach to restoring motor functions in poststroke states and Parkinson’s disease. The region of interest in most studies is in the secondary motor areas and the strength of the magnetic field is 3 T. We report here our studies on biocontrol using the fMRI signal from an area of the primary motor cortex associated with the operation of the right hand obtained using a 1.5-T tomograph and settings optimal for obtaining optimal images at this magnetic field strength. Subjects were 16 healthy subjects who took part in 30-min fMRI recording including 1) individual localization of the region of interest (rhythmic fist clenching test) and attempts to control its activity using 2) imaginary movements and 3) any cognitive strategy of the participant’s choice. Attempts to carry out self-control in both cases led to activation of the precentral, anterior cingulate, superior frontal, and inferior parietal gyri and Brodmann zone 6. fMRI signal maps for these tasks did not show any statistically significant differences and the activation zones showed little if any overlap with the region of interest, evidencing lack of success of sessions. The limitations of the experiments are discussed, as are factors with adverse influences on the effectiveness of biocontrol.
AB - Biocontrol based on fMRI signals from the motor area of the cortex is a potential approach to restoring motor functions in poststroke states and Parkinson’s disease. The region of interest in most studies is in the secondary motor areas and the strength of the magnetic field is 3 T. We report here our studies on biocontrol using the fMRI signal from an area of the primary motor cortex associated with the operation of the right hand obtained using a 1.5-T tomograph and settings optimal for obtaining optimal images at this magnetic field strength. Subjects were 16 healthy subjects who took part in 30-min fMRI recording including 1) individual localization of the region of interest (rhythmic fist clenching test) and attempts to control its activity using 2) imaginary movements and 3) any cognitive strategy of the participant’s choice. Attempts to carry out self-control in both cases led to activation of the precentral, anterior cingulate, superior frontal, and inferior parietal gyri and Brodmann zone 6. fMRI signal maps for these tasks did not show any statistically significant differences and the activation zones showed little if any overlap with the region of interest, evidencing lack of success of sessions. The limitations of the experiments are discussed, as are factors with adverse influences on the effectiveness of biocontrol.
KW - neurobiocontrol
KW - primary motor area
KW - real-time fMRI
UR - http://www.scopus.com/inward/record.url?scp=85046013374&partnerID=8YFLogxK
U2 - 10.1007/s11055-018-0588-2
DO - 10.1007/s11055-018-0588-2
M3 - Article
AN - SCOPUS:85046013374
VL - 48
SP - 474
EP - 482
JO - Neuroscience and Behavioral Physiology
JF - Neuroscience and Behavioral Physiology
SN - 0097-0549
IS - 4
ER -
ID: 12916683