Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Essential systemic hypertension : Genetics, clinics, experiment. / Markel, A. L.
в: Russian Journal of Cardiology, Том 150, № 10, 2017, стр. 133-139.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Essential systemic hypertension
T2 - Genetics, clinics, experiment
AU - Markel, A. L.
PY - 2017
Y1 - 2017
N2 - The lecture is focused on the exploration of genetic and physiological mechanisms of essential systemic hypertension (ESH). A very brief historic review is provided on the first clinical meanings of the ESH. Then some speculation provided, on its etiology, evolutionary-genetic roots regarding the formation of the main BP regulation systems. More detailed, the data is shown on genetic base of hypertensive conditions and ESH. Also, some discussion given on the monogenic forms of arterial hypertension and polygenic fundamentals of ESH, which is the most among hypertension conditions of human. Modern methods considered for genetic origins of ESH evaluation, and a necessity is underlined for the main etiological factors revealing — as of their interrelation for development of rational treatment and prevention methods against ESH.
AB - The lecture is focused on the exploration of genetic and physiological mechanisms of essential systemic hypertension (ESH). A very brief historic review is provided on the first clinical meanings of the ESH. Then some speculation provided, on its etiology, evolutionary-genetic roots regarding the formation of the main BP regulation systems. More detailed, the data is shown on genetic base of hypertensive conditions and ESH. Also, some discussion given on the monogenic forms of arterial hypertension and polygenic fundamentals of ESH, which is the most among hypertension conditions of human. Modern methods considered for genetic origins of ESH evaluation, and a necessity is underlined for the main etiological factors revealing — as of their interrelation for development of rational treatment and prevention methods against ESH.
KW - Clinical data
KW - Essential hypertension
KW - Evolution origin
KW - Genetic determination
UR - http://www.scopus.com/inward/record.url?scp=85034952706&partnerID=8YFLogxK
U2 - 10.15829/1560-4071-2017-10-133-139
DO - 10.15829/1560-4071-2017-10-133-139
M3 - Article
AN - SCOPUS:85034952706
VL - 150
SP - 133
EP - 139
JO - Российский кардиологический журнал
JF - Российский кардиологический журнал
SN - 1560-4071
IS - 10
ER -
ID: 8798342