Enzymatic esterification of saturated fatty acids with aliphatic alcohols as an alternative method of a low-temperature synthesis of esters

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Enzymatic esterification of saturated fatty acids with aliphatic alcohols as an alternative method of a low-temperature synthesis of esters. / Perminova, L. V.; Kovalenko, G. A.; Chukanov, N. V. и др.

в: Russian Chemical Bulletin, Том 66, № 11, 01.11.2017, стр. 2194-2197.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

BibTeX

@article{df6a2054a0d44249aa8d121bffb64f31,

title = "Enzymatic esterification of saturated fatty acids with aliphatic alcohols as an alternative method of a low-temperature synthesis of esters",

abstract = "low-temperature synthesis of saturated fatty acid esters with aliphatic alcohols by enzymatic esterification in the presence of heterogeneous biоcatalysts was suggested. The biоcatalysts were prepared by immobilization of recombinant rPichia/lip lipase on mesoporous silica. A comparison of the reaction rates was used to make up a matrix of biоcatalyst activities and determine a pair of acid/alcohol substrates, for which a maximum esterification rate was observed. A high activity of biоcatalysts was observed in the esterification of fatty acids with seven or more carbon atoms in the molecule. The rate of esterification of fatty acids with primary alcohols (n-C3—C16 or iso-С5) was two orders of magnitude higher than that with secondary alcohols (sec-С3—С4). The silica-immobilized rPichia/lip lipase possessed a high operational stability; the biocatalyst operated without loss of activity for hun-dreds of hours at 18—22 °С in a non-traditional for enzymes medium of organic solvents.",

keywords = "aliphatic alcohols, biоcatalyst, esterification, fatty acids, lipase, biocatalyst, LIPASE, SILICA",

author = "Perminova, {L. V.} and Kovalenko, {G. A.} and Chukanov, {N. V.} and Patrushev, {Yu V.}",

year = "2017",

month = nov,

day = "1",

doi = "10.1007/s11172-017-2002-6",

language = "English",

volume = "66",

pages = "2194--2197",

journal = "Russian Chemical Bulletin",

issn = "1066-5285",

publisher = "Springer Nature",

number = "11",

}

RIS

TY - JOUR

T1 - Enzymatic esterification of saturated fatty acids with aliphatic alcohols as an alternative method of a low-temperature synthesis of esters

AU - Perminova, L. V.

AU - Kovalenko, G. A.

AU - Chukanov, N. V.

AU - Patrushev, Yu V.

PY - 2017/11/1

Y1 - 2017/11/1

N2 - low-temperature synthesis of saturated fatty acid esters with aliphatic alcohols by enzymatic esterification in the presence of heterogeneous biоcatalysts was suggested. The biоcatalysts were prepared by immobilization of recombinant rPichia/lip lipase on mesoporous silica. A comparison of the reaction rates was used to make up a matrix of biоcatalyst activities and determine a pair of acid/alcohol substrates, for which a maximum esterification rate was observed. A high activity of biоcatalysts was observed in the esterification of fatty acids with seven or more carbon atoms in the molecule. The rate of esterification of fatty acids with primary alcohols (n-C3—C16 or iso-С5) was two orders of magnitude higher than that with secondary alcohols (sec-С3—С4). The silica-immobilized rPichia/lip lipase possessed a high operational stability; the biocatalyst operated without loss of activity for hun-dreds of hours at 18—22 °С in a non-traditional for enzymes medium of organic solvents.

AB - low-temperature synthesis of saturated fatty acid esters with aliphatic alcohols by enzymatic esterification in the presence of heterogeneous biоcatalysts was suggested. The biоcatalysts were prepared by immobilization of recombinant rPichia/lip lipase on mesoporous silica. A comparison of the reaction rates was used to make up a matrix of biоcatalyst activities and determine a pair of acid/alcohol substrates, for which a maximum esterification rate was observed. A high activity of biоcatalysts was observed in the esterification of fatty acids with seven or more carbon atoms in the molecule. The rate of esterification of fatty acids with primary alcohols (n-C3—C16 or iso-С5) was two orders of magnitude higher than that with secondary alcohols (sec-С3—С4). The silica-immobilized rPichia/lip lipase possessed a high operational stability; the biocatalyst operated without loss of activity for hun-dreds of hours at 18—22 °С in a non-traditional for enzymes medium of organic solvents.

KW - aliphatic alcohols

KW - biоcatalyst

KW - esterification

KW - fatty acids

KW - lipase

KW - biocatalyst

KW - LIPASE

KW - SILICA

UR - http://www.scopus.com/inward/record.url?scp=85044000512&partnerID=8YFLogxK

U2 - 10.1007/s11172-017-2002-6

DO - 10.1007/s11172-017-2002-6

M3 - Article

AN - SCOPUS:85044000512

VL - 66

SP - 2194

EP - 2197

JO - Russian Chemical Bulletin

JF - Russian Chemical Bulletin

SN - 1066-5285

IS - 11

ER -

ID: 12179129