TY - JOUR

T1 - Effect of New Antiviral Agent Camphecin on Behavior of Mice

AU - Babina, A. V.

AU - Lavrinenko, V. A.

AU - Yarovaya, O. I.

AU - Salakhutdinov, N. F.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - We studied the effect of camphecin (1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene-aminoethanol) on mouse behavior in the open-field test. Camphecin possesses antiviral activity and inhibits viral replication, but its influence on the nervous system is poorly studied. Single camphecin injection produced no significant changes in behavioral patterns. Chronic camphecin administration (5 times over 2 weeks) to mice of different strains had no significant influence on open field behavior (motor, exploratory activity, anxiety, emotional state and vegetative functions). The findings are discussed in the context of neutral influence of camphecin on animal behavior.

AB - We studied the effect of camphecin (1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene-aminoethanol) on mouse behavior in the open-field test. Camphecin possesses antiviral activity and inhibits viral replication, but its influence on the nervous system is poorly studied. Single camphecin injection produced no significant changes in behavioral patterns. Chronic camphecin administration (5 times over 2 weeks) to mice of different strains had no significant influence on open field behavior (motor, exploratory activity, anxiety, emotional state and vegetative functions). The findings are discussed in the context of neutral influence of camphecin on animal behavior.

KW - anxiety

KW - camphecin

KW - locomotor activity

UR - http://www.scopus.com/inward/record.url?scp=85009488851&partnerID=8YFLogxK

U2 - 10.1007/s10517-017-3612-6

DO - 10.1007/s10517-017-3612-6

M3 - Article

C2 - 28091927

AN - SCOPUS:85009488851

VL - 162

SP - 346

EP - 348

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

SN - 0007-4888

IS - 3

ER -