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Effect of hypomorphic mutation in Trithorax-like gene on Drosophila melanogaster oogenesis. / Ogienko, A. A.; Karagodin, D. A.; Fedorova, S. A. и др.

в: Ontogenez., Том 37, № 3, 05.2006, стр. 211-220.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Ogienko, AA, Karagodin, DA, Fedorova, SA, Fedorova, EV, Lashina, VV & Baricheva, EM 2006, 'Effect of hypomorphic mutation in Trithorax-like gene on Drosophila melanogaster oogenesis', Ontogenez., Том. 37, № 3, стр. 211-220.

APA

Ogienko, A. A., Karagodin, D. A., Fedorova, S. A., Fedorova, E. V., Lashina, V. V., & Baricheva, E. M. (2006). Effect of hypomorphic mutation in Trithorax-like gene on Drosophila melanogaster oogenesis. Ontogenez., 37(3), 211-220.

Vancouver

Ogienko AA, Karagodin DA, Fedorova SA, Fedorova EV, Lashina VV, Baricheva EM. Effect of hypomorphic mutation in Trithorax-like gene on Drosophila melanogaster oogenesis. Ontogenez. 2006 май;37(3):211-220.

Author

Ogienko, A. A. ; Karagodin, D. A. ; Fedorova, S. A. и др. / Effect of hypomorphic mutation in Trithorax-like gene on Drosophila melanogaster oogenesis. в: Ontogenez. 2006 ; Том 37, № 3. стр. 211-220.

BibTeX

@article{76183f6ccc064a0a866acd3bd30ecde0,
title = "Effect of hypomorphic mutation in Trithorax-like gene on Drosophila melanogaster oogenesis",
abstract = "We generated and characterized a new hypomorphic mutation of Drosophila melanogaster Trithorax-like (Trl) gene named Trl362. The Trl362 homozygous females are sterile and lay a small number of eggs; most embryos die at the early developmental stages. The transcriptional Trl level of adult Trl362 females was markedly lowered. Little or no GAGA protein, encoded by Trl@, was detected in the nurse cell nuclei. The ovaries of Trl362 females showed impairments, such considerable changes in the structure of both ovarioles and individual egg chambers. We believe that the observed ovarian defects in Trl362 mutants are mostly due to a decreased amount of GAGA protein in the germline cells. An increase of GAGA-519 protein caused by introduction of hsp83:GAGA-519 transgene against Trl362 background rescued partially the female fertility. It may well be that a decrease of GAGA protein in Trl362 germline cells leads to a defective expression of the genes regulated by transcription factor GAGA, whose products are essential for normal Drosophila oogenesis.",
author = "Ogienko, {A. A.} and Karagodin, {D. A.} and Fedorova, {S. A.} and Fedorova, {E. V.} and Lashina, {V. V.} and Baricheva, {E. M.}",
year = "2006",
month = may,
language = "English",
volume = "37",
pages = "211--220",
journal = "Ontogenez",
issn = "0475-1450",
publisher = "Izdatel'stvo Nauka",
number = "3",

}

RIS

TY - JOUR

T1 - Effect of hypomorphic mutation in Trithorax-like gene on Drosophila melanogaster oogenesis

AU - Ogienko, A. A.

AU - Karagodin, D. A.

AU - Fedorova, S. A.

AU - Fedorova, E. V.

AU - Lashina, V. V.

AU - Baricheva, E. M.

PY - 2006/5

Y1 - 2006/5

N2 - We generated and characterized a new hypomorphic mutation of Drosophila melanogaster Trithorax-like (Trl) gene named Trl362. The Trl362 homozygous females are sterile and lay a small number of eggs; most embryos die at the early developmental stages. The transcriptional Trl level of adult Trl362 females was markedly lowered. Little or no GAGA protein, encoded by Trl@, was detected in the nurse cell nuclei. The ovaries of Trl362 females showed impairments, such considerable changes in the structure of both ovarioles and individual egg chambers. We believe that the observed ovarian defects in Trl362 mutants are mostly due to a decreased amount of GAGA protein in the germline cells. An increase of GAGA-519 protein caused by introduction of hsp83:GAGA-519 transgene against Trl362 background rescued partially the female fertility. It may well be that a decrease of GAGA protein in Trl362 germline cells leads to a defective expression of the genes regulated by transcription factor GAGA, whose products are essential for normal Drosophila oogenesis.

AB - We generated and characterized a new hypomorphic mutation of Drosophila melanogaster Trithorax-like (Trl) gene named Trl362. The Trl362 homozygous females are sterile and lay a small number of eggs; most embryos die at the early developmental stages. The transcriptional Trl level of adult Trl362 females was markedly lowered. Little or no GAGA protein, encoded by Trl@, was detected in the nurse cell nuclei. The ovaries of Trl362 females showed impairments, such considerable changes in the structure of both ovarioles and individual egg chambers. We believe that the observed ovarian defects in Trl362 mutants are mostly due to a decreased amount of GAGA protein in the germline cells. An increase of GAGA-519 protein caused by introduction of hsp83:GAGA-519 transgene against Trl362 background rescued partially the female fertility. It may well be that a decrease of GAGA protein in Trl362 germline cells leads to a defective expression of the genes regulated by transcription factor GAGA, whose products are essential for normal Drosophila oogenesis.

UR - http://www.scopus.com/inward/record.url?scp=33746056512&partnerID=8YFLogxK

M3 - Article

C2 - 16813221

AN - SCOPUS:33746056512

VL - 37

SP - 211

EP - 220

JO - Ontogenez

JF - Ontogenez

SN - 0475-1450

IS - 3

ER -

ID: 25440126