Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Determination of the Microelement Composition of Biopsy Material of Red Bone Marrow in Patients with Hemoblastoses by the SR–XRF Method. / Trunova, V. A.; Pospelova, T. I.; Voytko, M. S. и др.
в: Journal of Surface Investigation, Том 19, № 1, 25.06.2025, стр. 218-223.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Determination of the Microelement Composition of Biopsy Material of Red Bone Marrow in Patients with Hemoblastoses by the SR–XRF Method
AU - Trunova, V. A.
AU - Pospelova, T. I.
AU - Voytko, M. S.
AU - Krupovich, E. S.
AU - Soldatova, G. S.
AU - Kuzmin, R. O.
AU - Tsigulev, K. S.
N1 - The development of the method for sample preparation of whole red bone marrow for SRXRF was supported by the Ministry of Science and Higher Education of the Russian Federation within the governmental order for SRF SKIF Boreskov Institute of Catalysis (project FWUR-2024-0040). Elemental analysis of biopsy material of red bone marrow of patients with hemoblastoses by the SRXRF method was carried out with the support of the Ministry of Science and Higher Education of the Russian Federation (project no. 121031700314-5). Determination of the Microelement Composition of Biopsy Material of Red Bone Marrow in Patients with Hemoblastoses by the SR–XRF Method / V. A. Trunova, T. I. Pospelova, M. S. Voytko [et al.] // Journal of Surface Investigation: X-Ray, Synchrotron and Neutron Techniques. – 2025. – Vol. 19, No. 1. – P. 218-223. – DOI 10.1134/S1027451025700326.
PY - 2025/6/25
Y1 - 2025/6/25
N2 - Abstract: Personalized medicine is a modern concept aimed at individualization of patient therapy. The relevance of the search and identification of new highly sensitive and specific prognostic markers in patients with hemoblastoses is due to the leading positions in the incidence and mortality rate among young working-age population, which gives the problem special socio-economic significance. The study is aimed at studying the content of trace elements in biopsy material (red bone marrow) of patients with hemoblastoses at the onset of the disease and after chemoradiation therapy. Using the method of X-ray fluorescence analysis and synchrotron radiation, it is possible to simultaneously determine more than 25 chemical elements in a low-mass sample with non-destructive sample preparation. Difference in the concentrations of 10 elements (S, K, Ca, Cu, Zn, Fe, Se, Br, Rb, and Cd) in patients with two pathologies, lymphoma and leukemia, is considered.
AB - Abstract: Personalized medicine is a modern concept aimed at individualization of patient therapy. The relevance of the search and identification of new highly sensitive and specific prognostic markers in patients with hemoblastoses is due to the leading positions in the incidence and mortality rate among young working-age population, which gives the problem special socio-economic significance. The study is aimed at studying the content of trace elements in biopsy material (red bone marrow) of patients with hemoblastoses at the onset of the disease and after chemoradiation therapy. Using the method of X-ray fluorescence analysis and synchrotron radiation, it is possible to simultaneously determine more than 25 chemical elements in a low-mass sample with non-destructive sample preparation. Difference in the concentrations of 10 elements (S, K, Ca, Cu, Zn, Fe, Se, Br, Rb, and Cd) in patients with two pathologies, lymphoma and leukemia, is considered.
KW - X-ray fluorescence analysis
KW - acute leukemia
KW - biopsy material
KW - hemoblastoses
KW - lymphoma
KW - personalized medicine
KW - red bone marrow
KW - synchrotron radiation
KW - trace elements
UR - https://www.mendeley.com/catalogue/e866e8c4-d88f-3d45-9b63-0fab0b02e891/
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105009351607&origin=inward
UR - https://www.elibrary.ru/item.asp?id=82550169
U2 - 10.1134/S1027451025700326
DO - 10.1134/S1027451025700326
M3 - Article
VL - 19
SP - 218
EP - 223
JO - Journal of Surface Investigation
JF - Journal of Surface Investigation
SN - 1027-4510
IS - 1
ER -
ID: 68292809