Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Design and Visualization of DNA/RNA Nanostructures from Branched Oligonucleotides Using Blender Software. / Bakulina, A. Yu; Rad’kova, Z. V.; Burakova, E. A. и др.
в: Russian Journal of Bioorganic Chemistry, Том 45, № 6, 01.11.2019, стр. 608-618.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Design and Visualization of DNA/RNA Nanostructures from Branched Oligonucleotides Using Blender Software
AU - Bakulina, A. Yu
AU - Rad’kova, Z. V.
AU - Burakova, E. A.
AU - Benassi, E.
AU - Zatsepin, T. S.
AU - Fokina, A. A.
AU - Stetsenko, D. A.
N1 - Publisher Copyright: © 2019, Pleiades Publishing, Ltd.
PY - 2019/11/1
Y1 - 2019/11/1
N2 - Recently, three-dimensional nucleic acid nanostructures have attracted great interest, which have been made available through the DNA origami technique. We have proposed a different way of constructing nucleic acid nanoobjects, namely, template-directed assembly employing branched oligonucleotides as templates and building blocks, which include nonnucleotidic linkers, particularly, branching units for connecting three or more oligonucleotide chains. For the design and 3D modelling of such nanostructures as DNA tetrahedron, DNA cube and DNA fullerene C24, we have used Blender software. As we found, Blender not only allows one to visualize complex DNA and RNA nanostructures, but also helps to choose the parameters for their synthesis.
AB - Recently, three-dimensional nucleic acid nanostructures have attracted great interest, which have been made available through the DNA origami technique. We have proposed a different way of constructing nucleic acid nanoobjects, namely, template-directed assembly employing branched oligonucleotides as templates and building blocks, which include nonnucleotidic linkers, particularly, branching units for connecting three or more oligonucleotide chains. For the design and 3D modelling of such nanostructures as DNA tetrahedron, DNA cube and DNA fullerene C24, we have used Blender software. As we found, Blender not only allows one to visualize complex DNA and RNA nanostructures, but also helps to choose the parameters for their synthesis.
KW - branched oligonucleotides
KW - click chemistry
KW - computer modelling
KW - DNA nanotechnology
KW - nucleic acids
KW - solid-phase synthesis
KW - template-directed assembly
UR - http://www.scopus.com/inward/record.url?scp=85077906395&partnerID=8YFLogxK
U2 - 10.1134/S1068162019060062
DO - 10.1134/S1068162019060062
M3 - Article
AN - SCOPUS:85077906395
VL - 45
SP - 608
EP - 618
JO - Russian Journal of Bioorganic Chemistry
JF - Russian Journal of Bioorganic Chemistry
SN - 1068-1620
IS - 6
ER -
ID: 23187986