TY - JOUR

T1 - Correlation of the organic sorbents texture with chromatographic characteristics of monolithic HPLC columns based on 1-vinyl-2-pyrrolidone

AU - Sotnikova, Yulia S.

AU - Patrushev, Yuri V.

AU - Sidelnikov, Vladimir N.

N1 - Funding Information: The reported study was funded by the Ministry of Science and Higher Education of the Russian Federation within the governmental order for Boreskov lnstitute of Catalysis (project AAAA-A21-121011390053-4). Publisher Copyright: © 2021 Elsevier B.V.

PY - 2022/4

Y1 - 2022/4

N2 - Monolithic sorbents based on styrene/divinylbenzene/1-vinyl-2-pyrrolidone copolymer have been synthesized inside the glass tubes with the inner diameter of 2 mm. The effect of the porogenic solvent nature and divinylbenzene content on the textural and chromatographic properties of sorbents was studied. Polypropylene glycol with the molecular weight 2025 g/mol and triblock copolymer Pluronic 10R5 (poly(propylene glycol)-block-poly(ethylene glycol)-block-poly(propylene glycol)) with the molecular weight 2000 g/mol were found to be the most suitable porogenic solvents. The fraction of divinylbenzene in the initial polymerization mixture was shown to affect the textural characteristics of sorbents (specific surface area, pore size and volume). The dependence of hydrodynamic permeability and columns loading capacity on divinylbenzene content in the initial reaction mixture was elucidated. Separation examples for the prepared columns are given.

AB - Monolithic sorbents based on styrene/divinylbenzene/1-vinyl-2-pyrrolidone copolymer have been synthesized inside the glass tubes with the inner diameter of 2 mm. The effect of the porogenic solvent nature and divinylbenzene content on the textural and chromatographic properties of sorbents was studied. Polypropylene glycol with the molecular weight 2025 g/mol and triblock copolymer Pluronic 10R5 (poly(propylene glycol)-block-poly(ethylene glycol)-block-poly(propylene glycol)) with the molecular weight 2000 g/mol were found to be the most suitable porogenic solvents. The fraction of divinylbenzene in the initial polymerization mixture was shown to affect the textural characteristics of sorbents (specific surface area, pore size and volume). The dependence of hydrodynamic permeability and columns loading capacity on divinylbenzene content in the initial reaction mixture was elucidated. Separation examples for the prepared columns are given.

KW - 1-Vinyl-2-pyrrolidone

KW - Cross-linked porous polymer

KW - HPLC

KW - Monolithic columns

UR - http://www.scopus.com/inward/record.url?scp=85122571143&partnerID=8YFLogxK

U2 - 10.1016/j.microc.2021.107119

DO - 10.1016/j.microc.2021.107119

M3 - Article

AN - SCOPUS:85122571143

VL - 175

JO - Microchemical Journal

JF - Microchemical Journal

SN - 0026-265X

M1 - 107119

ER -