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Coordination compounds of Co(II) and Cu(II) halides with 2,4-dimethyl-1,2,4-triazolo[1,5-a]benzimidazole. / Dyukova, I. I.; Lavrenova, L. G.; Kuz'menko, T. A. и др.
в: Inorganica Chimica Acta, Том 486, 24.02.2019, стр. 406-411.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Coordination compounds of Co(II) and Cu(II) halides with 2,4-dimethyl-1,2,4-triazolo[1,5-a]benzimidazole
AU - Dyukova, I. I.
AU - Lavrenova, L. G.
AU - Kuz'menko, T. A.
AU - Komarov, V. Yu
AU - Sukhikh, T. S.
AU - Vorontsova, E. V.
N1 - Publisher Copyright: © 2018 Elsevier B.V.
PY - 2019/2/24
Y1 - 2019/2/24
N2 - Coordination compounds based on cobalt(II) and copper(II) halides with 2,4-dimethyl-1,2,4-triazolo[1,5-a]benzimidazole (L) of composition [ML2Cl2] (where M = Co2+ (I) or Cu2+ (II)) and [CuL2Br2] (III) were synthesised. The compounds were characterised by single-crystal X-ray diffraction (XRD) analysis, UV–Vis spectroscopy (diffuse reflectance spectra, DRS) and infrared (IR) spectroscopy. Via XRD structural analysis, crystal structures were determined for [CoL2Cl2] (I), [CuL2Cl2] (II) and [Cu2L2(µ-Cl)2Cl2(H2O)2] (IIa). Cytotoxic effects of the complexes and ligand on cell line Hep-2 were studied, and it was found that the formation of a copper(II) complex with L considerably enhances cytotoxicity.
AB - Coordination compounds based on cobalt(II) and copper(II) halides with 2,4-dimethyl-1,2,4-triazolo[1,5-a]benzimidazole (L) of composition [ML2Cl2] (where M = Co2+ (I) or Cu2+ (II)) and [CuL2Br2] (III) were synthesised. The compounds were characterised by single-crystal X-ray diffraction (XRD) analysis, UV–Vis spectroscopy (diffuse reflectance spectra, DRS) and infrared (IR) spectroscopy. Via XRD structural analysis, crystal structures were determined for [CoL2Cl2] (I), [CuL2Cl2] (II) and [Cu2L2(µ-Cl)2Cl2(H2O)2] (IIa). Cytotoxic effects of the complexes and ligand on cell line Hep-2 were studied, and it was found that the formation of a copper(II) complex with L considerably enhances cytotoxicity.
KW - 2,4-Dimethyl-1,2,4-triazolo[1,5-a]benzimidazole
KW - 3d-Metal coordination compounds
KW - Cytotoxicity
KW - UV–Vis/IR spectroscopy
KW - XRD structural analysis
KW - MOLECULAR-STRUCTURE
KW - UV-Vis/IR spectroscopy
KW - COMPLEXES
KW - ANTIBACTERIAL
KW - CRYSTAL
KW - 1,2,4-TRIAZOLE
KW - PLATINUM(II)
KW - BENZIMIDAZOLE
KW - IMIDAZOLE
KW - ANTIMICROBIAL ACTIVITY
KW - THIABENDAZOLE
UR - http://www.scopus.com/inward/record.url?scp=85056241948&partnerID=8YFLogxK
U2 - 10.1016/j.ica.2018.10.064
DO - 10.1016/j.ica.2018.10.064
M3 - Article
AN - SCOPUS:85056241948
VL - 486
SP - 406
EP - 411
JO - Inorganica Chimica Acta
JF - Inorganica Chimica Acta
SN - 0020-1693
ER -
ID: 17407969