TY - JOUR

T1 - Comparative chromosome mapping of musk Ox and the X chromosome among some bovidae species

AU - Proskuryakova, Anastasia A.

AU - Kulemzina, Anastasia I.

AU - Perelman, Polina L.

AU - Yudkin, Dmitry V.

AU - Lemskaya, Natalya A.

AU - Okhlopkov, Innokentii M.

AU - Kirillin, Egor V.

AU - Farré, Marta

AU - Larkin, Denis M.

AU - Roelke-Parker, Melody E.

AU - O’Brien, Stephen J.

AU - Bush, Mitchell

AU - Graphodatsky, Alexander S.

N1 - Publisher Copyright: © 2019 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2019/10/29

Y1 - 2019/10/29

N2 - Bovidae, the largest family in Pecora infraorder, are characterized by a striking variability in diploid number of chromosomes between species and among individuals within a species. The bovid X chromosome is also remarkably variable, with several morphological types in the family. Here we built a detailed chromosome map of musk ox (Ovibos moschatus), a relic species originating from Pleistocene megafauna, with dromedary and human probes using chromosome painting. We trace chromosomal rearrangements during Bovidae evolution by comparing species already studied by chromosome painting. The musk ox karyotype differs from the ancestral pecoran karyotype by six fusions, one fission, and three inversions. We discuss changes in pecoran ancestral karyotype in the light of new painting data. Variations in the X chromosome structure of four bovid species nilgai bull (Boselaphus tragocamelus), saola (Pseudoryx nghetinhensis), gaur (Bos gaurus), and Kirk’s Dikdik (Madoqua kirkii) were further analyzed using 26 cattle BAC-clones. We found the duplication on the X in saola. We show main rearrangements leading to the formation of four types of bovid X: Bovinae type with derived cattle subtype formed by centromere reposition and Antilopinae type with Caprini subtype formed by inversion in XSB3.

AB - Bovidae, the largest family in Pecora infraorder, are characterized by a striking variability in diploid number of chromosomes between species and among individuals within a species. The bovid X chromosome is also remarkably variable, with several morphological types in the family. Here we built a detailed chromosome map of musk ox (Ovibos moschatus), a relic species originating from Pleistocene megafauna, with dromedary and human probes using chromosome painting. We trace chromosomal rearrangements during Bovidae evolution by comparing species already studied by chromosome painting. The musk ox karyotype differs from the ancestral pecoran karyotype by six fusions, one fission, and three inversions. We discuss changes in pecoran ancestral karyotype in the light of new painting data. Variations in the X chromosome structure of four bovid species nilgai bull (Boselaphus tragocamelus), saola (Pseudoryx nghetinhensis), gaur (Bos gaurus), and Kirk’s Dikdik (Madoqua kirkii) were further analyzed using 26 cattle BAC-clones. We found the duplication on the X in saola. We show main rearrangements leading to the formation of four types of bovid X: Bovinae type with derived cattle subtype formed by centromere reposition and Antilopinae type with Caprini subtype formed by inversion in XSB3.

KW - BAC-clones

KW - Chromosome painting

KW - Gaur

KW - Kirk’s dikdik

KW - Musk ox

KW - Nilgai bull

KW - Saola

KW - LINKAGE MAP

KW - nilgai bull

KW - BEHAVIOR

KW - gaur

KW - SHEEP

KW - HOMOLOGIES

KW - RIVER BUFFALO

KW - CYTOGENETIC ANALYSIS

KW - ANTELOPE

KW - chromosome painting

KW - EVOLUTION

KW - CONSERVATION

KW - saola

KW - Kirk's Dikdik

KW - FISH

KW - musk ox

UR - http://www.scopus.com/inward/record.url?scp=85074414352&partnerID=8YFLogxK

U2 - 10.3390/genes10110857

DO - 10.3390/genes10110857

M3 - Article

C2 - 31671864

AN - SCOPUS:85074414352

VL - 10

JO - Genes

JF - Genes

SN - 2073-4425

IS - 11

M1 - 857

ER -