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Characteristics of liver fibrosis associated with chronic Opisthorchis felineus infection in Syrian hamsters and humans. / Kovner, Anna V.; Pakharukova, Maria Y.; Maksimova, Galina A. и др.

в: Experimental and Molecular Pathology, Том 110, 104274, 01.10.2019, стр. 104274.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Kovner, AV, Pakharukova, MY, Maksimova, GA & Mordvinov, VA 2019, 'Characteristics of liver fibrosis associated with chronic Opisthorchis felineus infection in Syrian hamsters and humans', Experimental and Molecular Pathology, Том. 110, 104274, стр. 104274. https://doi.org/10.1016/j.yexmp.2019.104274

APA

Kovner, A. V., Pakharukova, M. Y., Maksimova, G. A., & Mordvinov, V. A. (2019). Characteristics of liver fibrosis associated with chronic Opisthorchis felineus infection in Syrian hamsters and humans. Experimental and Molecular Pathology, 110, 104274. [104274]. https://doi.org/10.1016/j.yexmp.2019.104274

Vancouver

Kovner AV, Pakharukova MY, Maksimova GA, Mordvinov VA. Characteristics of liver fibrosis associated with chronic Opisthorchis felineus infection in Syrian hamsters and humans. Experimental and Molecular Pathology. 2019 окт. 1;110:104274. 104274. Epub 2019 июнь 19. doi: 10.1016/j.yexmp.2019.104274

Author

Kovner, Anna V. ; Pakharukova, Maria Y. ; Maksimova, Galina A. и др. / Characteristics of liver fibrosis associated with chronic Opisthorchis felineus infection in Syrian hamsters and humans. в: Experimental and Molecular Pathology. 2019 ; Том 110. стр. 104274.

BibTeX

@article{f194212a383344fbad1da595a86b21f6,
title = "Characteristics of liver fibrosis associated with chronic Opisthorchis felineus infection in Syrian hamsters and humans",
abstract = "The food-borne liver trematode Opisthorchis felineus causes severe liver damage, including fibrosis. This study shows a comparison of the characteristics between cholangiofibrosis and periductal fibrosis in infected people and in the golden hamster as an experimental model. Comparative evaluation was carried out regarding collagen composition, the number of basic-producing cells, and extracellular-matrix degradation. The results revealed that characteristics of chronic opisthorchiasis due to O. felineus infection in humans and in Syrian hamsters are similar and include well-pronounced development of fibrotic complications in the liver parenchyma. Besides, a difference in fibrogenesis development was demonstrated between chronic O. felineus infection and noninfectious cholecystitis. In this study, we for the first time compared fibrogenesis between humans and model animals against the background of chronic O. felineus infection.",
keywords = "Cholecystitis, Fibrosis, Human, O. Felineus, Syrian hamster, CHOLANGIOCARCINOMA, PROTEIN, ABNORMALITIES, CURCUMIN, PERIDUCTAL FIBROSIS",
author = "Kovner, {Anna V.} and Pakharukova, {Maria Y.} and Maksimova, {Galina A.} and Mordvinov, {Viatcheslav A.}",
note = "Copyright {\textcopyright} 2019. Published by Elsevier Inc.",
year = "2019",
month = oct,
day = "1",
doi = "10.1016/j.yexmp.2019.104274",
language = "English",
volume = "110",
pages = "104274",
journal = "Experimental and Molecular Pathology",
issn = "0014-4800",
publisher = "Academic Press Inc.",

}

RIS

TY - JOUR

T1 - Characteristics of liver fibrosis associated with chronic Opisthorchis felineus infection in Syrian hamsters and humans

AU - Kovner, Anna V.

AU - Pakharukova, Maria Y.

AU - Maksimova, Galina A.

AU - Mordvinov, Viatcheslav A.

N1 - Copyright © 2019. Published by Elsevier Inc.

PY - 2019/10/1

Y1 - 2019/10/1

N2 - The food-borne liver trematode Opisthorchis felineus causes severe liver damage, including fibrosis. This study shows a comparison of the characteristics between cholangiofibrosis and periductal fibrosis in infected people and in the golden hamster as an experimental model. Comparative evaluation was carried out regarding collagen composition, the number of basic-producing cells, and extracellular-matrix degradation. The results revealed that characteristics of chronic opisthorchiasis due to O. felineus infection in humans and in Syrian hamsters are similar and include well-pronounced development of fibrotic complications in the liver parenchyma. Besides, a difference in fibrogenesis development was demonstrated between chronic O. felineus infection and noninfectious cholecystitis. In this study, we for the first time compared fibrogenesis between humans and model animals against the background of chronic O. felineus infection.

AB - The food-borne liver trematode Opisthorchis felineus causes severe liver damage, including fibrosis. This study shows a comparison of the characteristics between cholangiofibrosis and periductal fibrosis in infected people and in the golden hamster as an experimental model. Comparative evaluation was carried out regarding collagen composition, the number of basic-producing cells, and extracellular-matrix degradation. The results revealed that characteristics of chronic opisthorchiasis due to O. felineus infection in humans and in Syrian hamsters are similar and include well-pronounced development of fibrotic complications in the liver parenchyma. Besides, a difference in fibrogenesis development was demonstrated between chronic O. felineus infection and noninfectious cholecystitis. In this study, we for the first time compared fibrogenesis between humans and model animals against the background of chronic O. felineus infection.

KW - Cholecystitis

KW - Fibrosis

KW - Human

KW - O. Felineus

KW - Syrian hamster

KW - CHOLANGIOCARCINOMA

KW - PROTEIN

KW - ABNORMALITIES

KW - CURCUMIN

KW - PERIDUCTAL FIBROSIS

UR - http://www.scopus.com/inward/record.url?scp=85068868255&partnerID=8YFLogxK

U2 - 10.1016/j.yexmp.2019.104274

DO - 10.1016/j.yexmp.2019.104274

M3 - Article

C2 - 31226265

AN - SCOPUS:85068868255

VL - 110

SP - 104274

JO - Experimental and Molecular Pathology

JF - Experimental and Molecular Pathology

SN - 0014-4800

M1 - 104274

ER -

ID: 20825182