TY - GEN

T1 - Cardiac rhythm and conduction disturbances in patients with ankylosing spondylitis

AU - Akinshin, Andrey V.

AU - Omelchenko,

AU - Vitaliy, O.

AU - Korolev, Maxim A.

N1 - Publisher Copyright: © 2022 IEEE.

PY - 2022

Y1 - 2022

N2 - Aim of the study: The aim of this study was to investigate the association of clinical characteristics and treatment of ankylosing spondylitis with the presence of rhythm and conduction disturbances. Materials and methods: Forty six hospitalized patients diagnosed with ankylosing spondylitis meeting the 1984 New York criteria with excluded coronary artery disease were included in our study. Clinical methods of examination, laboratory methods of examination, electrocardiography, daily monitoring of electrocardiography were used. Results: Rhythm and conduction disturbances were found in 28.3% of patients. No statistically significant differences in ankylosing spondylitis (AS) clinical characteristics and treatment were obtained between groups with and without arrhythmia/conduction disturbances. Patients with early/advanced AS stage were more likely to have rhythm and conduction disturbances comparing with patients with late stage of AS (p=0.08). Arrhythmias and conduction disturbances were prevalent in patients, treated with TNF -blockers (p=0.06). Conclusions: Treatment of ankylosing spondylitis by TNF-blockers may be associated with formation of cardiac rhythm and conduction disturbances.

AB - Aim of the study: The aim of this study was to investigate the association of clinical characteristics and treatment of ankylosing spondylitis with the presence of rhythm and conduction disturbances. Materials and methods: Forty six hospitalized patients diagnosed with ankylosing spondylitis meeting the 1984 New York criteria with excluded coronary artery disease were included in our study. Clinical methods of examination, laboratory methods of examination, electrocardiography, daily monitoring of electrocardiography were used. Results: Rhythm and conduction disturbances were found in 28.3% of patients. No statistically significant differences in ankylosing spondylitis (AS) clinical characteristics and treatment were obtained between groups with and without arrhythmia/conduction disturbances. Patients with early/advanced AS stage were more likely to have rhythm and conduction disturbances comparing with patients with late stage of AS (p=0.08). Arrhythmias and conduction disturbances were prevalent in patients, treated with TNF -blockers (p=0.06). Conclusions: Treatment of ankylosing spondylitis by TNF-blockers may be associated with formation of cardiac rhythm and conduction disturbances.

KW - ankylosing spondylitis

KW - cardiac arrhythmia

KW - cardiac conduction disturbances

UR - http://www.scopus.com/inward/record.url?scp=85138471530&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/8ee1dfa3-e191-3b99-94cf-967b0e2b4a23/

U2 - 10.1109/CSGB56354.2022.9865540

DO - 10.1109/CSGB56354.2022.9865540

M3 - Conference contribution

AN - SCOPUS:85138471530

T3 - Proceedings - 2022 Ural-Siberian Conference on Computational Technologies in Cognitive Science, Genomics and Biomedicine, CSGB 2022

SP - 10

EP - 13

BT - Proceedings - 2022 Ural-Siberian Conference on Computational Technologies in Cognitive Science, Genomics and Biomedicine, CSGB 2022

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2022 Ural-Siberian Conference on Computational Technologies in Cognitive Science, Genomics and Biomedicine, CSGB 2022

Y2 - 7 July 2022 through 8 July 2022

ER -