Результаты исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › Рецензирование
Biophotonics approach for the study of leukocyte activation. / Chernova, Daria N.; Sokolovski, Sergei G.; Vorobev, Alexey Yu и др.
Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine. ред. / Valery V. Tuchin; Elina A. Genina. SPIE, 2020. 114570G (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Том 11457).Результаты исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › Рецензирование
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TY - GEN
T1 - Biophotonics approach for the study of leukocyte activation
AU - Chernova, Daria N.
AU - Sokolovski, Sergei G.
AU - Vorobev, Alexey Yu
AU - Moskalensky, Alexander E.
PY - 2020/4/9
Y1 - 2020/4/9
N2 - Leukocytes are the main cells of immune system, but also contribute to other systems and participate in pathogenesis of different diseases. In particular, leukocytes are involved in the progression of diabetic retinopathy due to their hyperactivation in diabetes. However, a connection between diabetes and the dysfunction of leukocytes is poorly understood. For a more complete picture, studies of the leukocytes activation under the influence of various substances are necessary. Arachidonic acid (AA) and its metabolites are the strongest activating factors of leukocytes. However, the studies involving AA are complicated because it is water-insoluble. Here we describe the method to study activation using photolabile analogs of AA.
AB - Leukocytes are the main cells of immune system, but also contribute to other systems and participate in pathogenesis of different diseases. In particular, leukocytes are involved in the progression of diabetic retinopathy due to their hyperactivation in diabetes. However, a connection between diabetes and the dysfunction of leukocytes is poorly understood. For a more complete picture, studies of the leukocytes activation under the influence of various substances are necessary. Arachidonic acid (AA) and its metabolites are the strongest activating factors of leukocytes. However, the studies involving AA are complicated because it is water-insoluble. Here we describe the method to study activation using photolabile analogs of AA.
KW - Arachidonic acid
KW - Biophotonics
KW - Caged arachidonic acid
KW - Dysfunction of leukocytes
KW - Intracellular calcium
KW - Jurkat cell
KW - Photolabile analogs
KW - Single cell optical control
KW - arachidonic acid
KW - dysfunction of leukocytes
KW - caged arachidonic acid
KW - single cell optical control
KW - biophotonics
KW - CALCIUM
KW - photolabile analogs
KW - intracellular calcium
UR - http://www.scopus.com/inward/record.url?scp=85084173115&partnerID=8YFLogxK
U2 - 10.1117/12.2560325
DO - 10.1117/12.2560325
M3 - Conference contribution
AN - SCOPUS:85084173115
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Saratov Fall Meeting 2019
A2 - Tuchin, Valery V.
A2 - Genina, Elina A.
PB - SPIE
T2 - 7th International Symposium on Optics and Biophotonics: Optical and Nano-Technologies for Biology and Medicine, SFM 2019
Y2 - 23 September 2019 through 27 September 2019
ER -
ID: 24228347