TY - JOUR

T1 - Associations of hyperactivity and inattention scores with theta and beta oscillatory dynamics of eeg in stop-signal task in healthy children 7–10 years old

AU - Bocharov, Andrey V.

AU - Savostyanov, Alexander N.

AU - Slobodskaya, Helena R.

AU - Tamozhnikov, Sergey S.

AU - Levin, Evgeny A.

AU - Saprigyn, Alexander E.

AU - Proshina, Ekaterina A.

AU - Astakhova, Tatiana N.

AU - Merkulova, Ekaterina A.

AU - Knyazev, Gennady G.

N1 - Funding Information: Funding: The study was supported by the Russian Foundation for Basic Research (RFBR) under Grant No. 18-29-13027, Grant No. 20-013-00404; the Russian Science Foundation grant number 16-18-00003; and budgetary funding of SRINM for basic scientific research (theme No. AAAA-A21-121011990039-2). The work of A.N. Savostyanov and A.E. Saprigyn was also supported by the budgetary funding of ICG SB RAS theme No. 0259-2021-0009. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021/10

Y1 - 2021/10

N2 - In the current study, we aimed to investigate the associations between the natural variability in hyperactivity and inattention scores, as well as their combination with EEG oscillatory responses in the Stop-Signal task in a sample of healthy children. During performance, the Stop-Signal task EEGs were recorded in 94 Caucasian children (40 girls) from 7 to 10 years. Hyperactivity/inattention and inattention scores positively correlated with RT variability. Hyperactivity/inattention and inattention scores negatively correlated with an increase in beta spectral power in the first 200 ms after presentation of the Go stimulus. Such results are in line with the lack of arousal model in ADHD children and can be associated with less sensory arousal in the early stages of perception in children with symptoms of inattention. The subsequent greater increase in theta rhythm at about 300 ms after presentation of the Go stimulus in children with higher inattention scores may be associated with increased attention processes and compensation for insufficient vigilance in the early stages of perception.

AB - In the current study, we aimed to investigate the associations between the natural variability in hyperactivity and inattention scores, as well as their combination with EEG oscillatory responses in the Stop-Signal task in a sample of healthy children. During performance, the Stop-Signal task EEGs were recorded in 94 Caucasian children (40 girls) from 7 to 10 years. Hyperactivity/inattention and inattention scores positively correlated with RT variability. Hyperactivity/inattention and inattention scores negatively correlated with an increase in beta spectral power in the first 200 ms after presentation of the Go stimulus. Such results are in line with the lack of arousal model in ADHD children and can be associated with less sensory arousal in the early stages of perception in children with symptoms of inattention. The subsequent greater increase in theta rhythm at about 300 ms after presentation of the Go stimulus in children with higher inattention scores may be associated with increased attention processes and compensation for insufficient vigilance in the early stages of perception.

KW - ADHD

KW - Beta oscillations

KW - Children

KW - Hyperactivity

KW - Inattention

KW - Stop-Signal task

KW - Theta oscillations

UR - http://www.scopus.com/inward/record.url?scp=85115794721&partnerID=8YFLogxK

U2 - 10.3390/biology10100946

DO - 10.3390/biology10100946

M3 - Article

C2 - 34681045

AN - SCOPUS:85115794721

VL - 10

JO - Biology

JF - Biology

SN - 2079-7737

IS - 10

M1 - 946

ER -