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Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus. / Prokhorova, Daria; Zhukova, Natalya; Lemza, Anna и др.

в: Viruses, Том 14, № 2, 437, 02.2022.

Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование

Harvard

Prokhorova, D, Zhukova, N, Lemza, A, Sergeeva, M, Amirkhanov, R & Stepanov, G 2022, 'Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus', Viruses, Том. 14, № 2, 437. https://doi.org/10.3390/v14020437

APA

Prokhorova, D., Zhukova, N., Lemza, A., Sergeeva, M., Amirkhanov, R., & Stepanov, G. (2022). Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus. Viruses, 14(2), [437]. https://doi.org/10.3390/v14020437

Vancouver

Prokhorova D, Zhukova N, Lemza A, Sergeeva M, Amirkhanov R, Stepanov G. Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus. Viruses. 2022 февр.;14(2):437. doi: 10.3390/v14020437

Author

Prokhorova, Daria ; Zhukova, Natalya ; Lemza, Anna и др. / Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus. в: Viruses. 2022 ; Том 14, № 2.

BibTeX

@article{77a98c7f88f54a909f2916a62e2b966b,
title = "Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus",
abstract = "Influenza A virus (IAV) causes a respiratory infection that affects millions of people of different age groups and can lead to acute respiratory distress syndrome. Currently, host genes, receptors, and other cellular components critical for IAV replication are actively studied. One of the most convenient and accessible genome-editing tools to facilitate these studies is the CRISPR/Cas9 system. This tool allows for regulating the expression of both viral and host cell genes to enhance or impair viral entry and replication. This review considers the effect of the genome editing system on specific target genes in cells (human and chicken) in terms of subsequent changes in the influenza virus life cycle and the efficiency of virus particle production.",
keywords = "Cell receptors, Cellular immune response, CRISPR/Cas9, CRISPR/Cas9 genome screening, Influenza virus, RNA processing factors, Cell Line, Humans, Gene Editing/methods, Virus Internalization, CRISPR-Cas Systems/genetics, Influenza A virus/genetics, Animals, Virus Replication, Chickens, Immunity, Cellular",
author = "Daria Prokhorova and Natalya Zhukova and Anna Lemza and Mariia Sergeeva and Rinat Amirkhanov and Grigory Stepanov",
note = "Funding Information: Funding: This research was supported within the framework of the state assignment of the ICBFM SB RAS [number 0245-2022-0002] and was supported by the RFBR [grant number 18-29-07073]. Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2022",
month = feb,
doi = "10.3390/v14020437",
language = "English",
volume = "14",
journal = "Viruses",
issn = "1999-4915",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "2",

}

RIS

TY - JOUR

T1 - Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus

AU - Prokhorova, Daria

AU - Zhukova, Natalya

AU - Lemza, Anna

AU - Sergeeva, Mariia

AU - Amirkhanov, Rinat

AU - Stepanov, Grigory

N1 - Funding Information: Funding: This research was supported within the framework of the state assignment of the ICBFM SB RAS [number 0245-2022-0002] and was supported by the RFBR [grant number 18-29-07073]. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2022/2

Y1 - 2022/2

N2 - Influenza A virus (IAV) causes a respiratory infection that affects millions of people of different age groups and can lead to acute respiratory distress syndrome. Currently, host genes, receptors, and other cellular components critical for IAV replication are actively studied. One of the most convenient and accessible genome-editing tools to facilitate these studies is the CRISPR/Cas9 system. This tool allows for regulating the expression of both viral and host cell genes to enhance or impair viral entry and replication. This review considers the effect of the genome editing system on specific target genes in cells (human and chicken) in terms of subsequent changes in the influenza virus life cycle and the efficiency of virus particle production.

AB - Influenza A virus (IAV) causes a respiratory infection that affects millions of people of different age groups and can lead to acute respiratory distress syndrome. Currently, host genes, receptors, and other cellular components critical for IAV replication are actively studied. One of the most convenient and accessible genome-editing tools to facilitate these studies is the CRISPR/Cas9 system. This tool allows for regulating the expression of both viral and host cell genes to enhance or impair viral entry and replication. This review considers the effect of the genome editing system on specific target genes in cells (human and chicken) in terms of subsequent changes in the influenza virus life cycle and the efficiency of virus particle production.

KW - Cell receptors

KW - Cellular immune response

KW - CRISPR/Cas9

KW - CRISPR/Cas9 genome screening

KW - Influenza virus

KW - RNA processing factors

KW - Cell Line

KW - Humans

KW - Gene Editing/methods

KW - Virus Internalization

KW - CRISPR-Cas Systems/genetics

KW - Influenza A virus/genetics

KW - Animals

KW - Virus Replication

KW - Chickens

KW - Immunity, Cellular

UR - http://www.scopus.com/inward/record.url?scp=85125165369&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/9cbb126e-d76f-3b74-803f-8b5fdc8bd929/

U2 - 10.3390/v14020437

DO - 10.3390/v14020437

M3 - Review article

C2 - 35216030

AN - SCOPUS:85125165369

VL - 14

JO - Viruses

JF - Viruses

SN - 1999-4915

IS - 2

M1 - 437

ER -

ID: 35599195