TY - JOUR

T1 - Application of Natural Polysaccharides in Pharmaceutics

AU - Khvostov, M. V.

AU - Tolstikova, T. G.

AU - Borisov, S. A.

AU - Dushkin, A. V.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Modern data are presented on the pharmaceutical application of natural polysaccharides, such as pullulan, alginates, hyaluronic acid, dextrans, pectin, chitosan, and arabinogalactan, which are already actively used or can be used in the future for optimizing different drug forms, water solubility and improving bioavailability. The emphasis on natural polysaccharides is made in relation to their good biocompatibility, biodegradation, hydrophilicity, good stability, safety, lack of toxicity, and adhesive properties. The indicated parameters are important and necessary for agents used for drug delivery into the human body.

AB - Modern data are presented on the pharmaceutical application of natural polysaccharides, such as pullulan, alginates, hyaluronic acid, dextrans, pectin, chitosan, and arabinogalactan, which are already actively used or can be used in the future for optimizing different drug forms, water solubility and improving bioavailability. The emphasis on natural polysaccharides is made in relation to their good biocompatibility, biodegradation, hydrophilicity, good stability, safety, lack of toxicity, and adhesive properties. The indicated parameters are important and necessary for agents used for drug delivery into the human body.

KW - alginates

KW - arabinogalactan

KW - chitosan

KW - dextrans

KW - hyaluronic acid

KW - increased bioavailability

KW - pectin

KW - polysaccharides

KW - pullulan

UR - http://www.scopus.com/inward/record.url?scp=85077872437&partnerID=8YFLogxK

U2 - 10.1134/S1068162019060219

DO - 10.1134/S1068162019060219

M3 - Review article

AN - SCOPUS:85077872437

VL - 45

SP - 438

EP - 450

JO - Russian Journal of Bioorganic Chemistry

JF - Russian Journal of Bioorganic Chemistry

SN - 1068-1620

IS - 6

ER -