Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Antiulcerogenic activity of borneol derivatives. / Borisova, M. S.; Yarovaya, O. I.; Semenova, M. D. и др.
в: Russian Chemical Bulletin, Том 67, № 3, 01.03.2018, стр. 558-561.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Antiulcerogenic activity of borneol derivatives
AU - Borisova, M. S.
AU - Yarovaya, O. I.
AU - Semenova, M. D.
AU - Tolstikova, T. G.
AU - Salakhutdinov, N. F.
PY - 2018/3/1
Y1 - 2018/3/1
N2 - Antiulcerogenic activity of borneol and its N-heterocyclic esters was investigated using indomethacin-induced gastric ulcer model. A considerable antiulcerogenic effect comparable to that shown by Omeprazole and Famotidine was found for two investigated compounds in the indomethacin-induced gastric ulcer model. Bornyl 2-piperazinoacetate, with a non-substituted piperazine moiety, showed maximum antiulcerogenic activity in the indomethacininduced gastric ulcer model and demonstrated a significant gastroprotective effect in the ethanol-induced gastric ulcer model comparable to the effect of Omeprazole.
AB - Antiulcerogenic activity of borneol and its N-heterocyclic esters was investigated using indomethacin-induced gastric ulcer model. A considerable antiulcerogenic effect comparable to that shown by Omeprazole and Famotidine was found for two investigated compounds in the indomethacin-induced gastric ulcer model. Bornyl 2-piperazinoacetate, with a non-substituted piperazine moiety, showed maximum antiulcerogenic activity in the indomethacininduced gastric ulcer model and demonstrated a significant gastroprotective effect in the ethanol-induced gastric ulcer model comparable to the effect of Omeprazole.
KW - antiulcerogenic activity
KW - borneol derivatives
UR - http://www.scopus.com/inward/record.url?scp=85049339495&partnerID=8YFLogxK
U2 - 10.1007/s11172-018-2110-y
DO - 10.1007/s11172-018-2110-y
M3 - Article
AN - SCOPUS:85049339495
VL - 67
SP - 558
EP - 561
JO - Russian Chemical Bulletin
JF - Russian Chemical Bulletin
SN - 1066-5285
IS - 3
ER -
ID: 14316629