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Antioxidative properties of nitroxyl radicals and hydroxyamines in reactions with triplet and deaminated kynurenine. / Yan'shole, V. V.; Kirilyuk, I. A.; Grigor'ev, I. A. и др.

в: Russian Chemical Bulletin, Том 59, № 1, 6, 01.2010, стр. 66-74.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

Harvard

Yan'shole, VV, Kirilyuk, IA, Grigor'ev, IA, Morozov, SV & Tsentalovich, YP 2010, 'Antioxidative properties of nitroxyl radicals and hydroxyamines in reactions with triplet and deaminated kynurenine', Russian Chemical Bulletin, Том. 59, № 1, 6, стр. 66-74. https://doi.org/10.1007/s11172-010-0046-y

APA

Vancouver

Yan'shole VV, Kirilyuk IA, Grigor'ev IA, Morozov SV, Tsentalovich YP. Antioxidative properties of nitroxyl radicals and hydroxyamines in reactions with triplet and deaminated kynurenine. Russian Chemical Bulletin. 2010 янв.;59(1):66-74. 6. doi: 10.1007/s11172-010-0046-y

Author

Yan'shole, V. V. ; Kirilyuk, I. A. ; Grigor'ev, I. A. и др. / Antioxidative properties of nitroxyl radicals and hydroxyamines in reactions with triplet and deaminated kynurenine. в: Russian Chemical Bulletin. 2010 ; Том 59, № 1. стр. 66-74.

BibTeX

@article{062c09fdc85347beb0b285b1e7210d6e,
title = "Antioxidative properties of nitroxyl radicals and hydroxyamines in reactions with triplet and deaminated kynurenine",
abstract = "The reactions of triplet kynurenine and 4-(2-aminophenyl)-4-oxocrotonic acid, formed upon the thermal decomposition of kynurenine, with nitroxyl radicals and cyclic N-hydroxylamines were studied. Nitroxyl radicals were found to quench efficiently the triplet state of kynurenine (rate constant 3-6 ·108 L mol-1 s-1). The quenching proceeds via the spinexchange mechanism and affords no new products. Neither nitroxyl radicals, nor hydroxylamines react with 4-(2-aminophenyl)-4-oxocrotonic acid under conditions similar to physiological.",
keywords = "4-(2-aminophenyl)-4-oxocrotonic acid, Hydroxylamines, Kynurenine, Laser flash photolysis, Nitroxyl radicals, Quenching reactions, Triplet excited state",
author = "Yan'shole, {V. V.} and Kirilyuk, {I. A.} and Grigor'ev, {I. A.} and Morozov, {S. V.} and Tsentalovich, {Yu P.}",
note = "This work was financially supported by the Federal Agency on Science and Innovations (State Contract No. 02.512.11.2278), the Russian Foundation for Basic Research (Project Nos 08 03 00539, 08 03 00432, and 07 03 00253), the Division of Chemistry and Materials Science of the Russian Academy of Sciences (Project No. 5.1.1), the Council on Grants at the President of the Russian Federation (State Support Program for Leading Scientific Schools, Grant NSh 3604.2008.3), the Russian Academy of Sciences (Program {"}Fundamental Sciences to Medicine,{"} Project No. 22), and the Government of Moscow (Program {"}New Methods and Technologies of Early Diagnostics and Treatment of Oncological and Other Dangerous Diseases{"}).",
year = "2010",
month = jan,
doi = "10.1007/s11172-010-0046-y",
language = "English",
volume = "59",
pages = "66--74",
journal = "Russian Chemical Bulletin",
issn = "1066-5285",
publisher = "Springer Nature",
number = "1",

}

RIS

TY - JOUR

T1 - Antioxidative properties of nitroxyl radicals and hydroxyamines in reactions with triplet and deaminated kynurenine

AU - Yan'shole, V. V.

AU - Kirilyuk, I. A.

AU - Grigor'ev, I. A.

AU - Morozov, S. V.

AU - Tsentalovich, Yu P.

N1 - This work was financially supported by the Federal Agency on Science and Innovations (State Contract No. 02.512.11.2278), the Russian Foundation for Basic Research (Project Nos 08 03 00539, 08 03 00432, and 07 03 00253), the Division of Chemistry and Materials Science of the Russian Academy of Sciences (Project No. 5.1.1), the Council on Grants at the President of the Russian Federation (State Support Program for Leading Scientific Schools, Grant NSh 3604.2008.3), the Russian Academy of Sciences (Program "Fundamental Sciences to Medicine," Project No. 22), and the Government of Moscow (Program "New Methods and Technologies of Early Diagnostics and Treatment of Oncological and Other Dangerous Diseases").

PY - 2010/1

Y1 - 2010/1

N2 - The reactions of triplet kynurenine and 4-(2-aminophenyl)-4-oxocrotonic acid, formed upon the thermal decomposition of kynurenine, with nitroxyl radicals and cyclic N-hydroxylamines were studied. Nitroxyl radicals were found to quench efficiently the triplet state of kynurenine (rate constant 3-6 ·108 L mol-1 s-1). The quenching proceeds via the spinexchange mechanism and affords no new products. Neither nitroxyl radicals, nor hydroxylamines react with 4-(2-aminophenyl)-4-oxocrotonic acid under conditions similar to physiological.

AB - The reactions of triplet kynurenine and 4-(2-aminophenyl)-4-oxocrotonic acid, formed upon the thermal decomposition of kynurenine, with nitroxyl radicals and cyclic N-hydroxylamines were studied. Nitroxyl radicals were found to quench efficiently the triplet state of kynurenine (rate constant 3-6 ·108 L mol-1 s-1). The quenching proceeds via the spinexchange mechanism and affords no new products. Neither nitroxyl radicals, nor hydroxylamines react with 4-(2-aminophenyl)-4-oxocrotonic acid under conditions similar to physiological.

KW - 4-(2-aminophenyl)-4-oxocrotonic acid

KW - Hydroxylamines

KW - Kynurenine

KW - Laser flash photolysis

KW - Nitroxyl radicals

KW - Quenching reactions

KW - Triplet excited state

UR - http://www.scopus.com/inward/record.url?scp=77955856339&partnerID=8YFLogxK

UR - https://www.elibrary.ru/item.asp?id=15329241

U2 - 10.1007/s11172-010-0046-y

DO - 10.1007/s11172-010-0046-y

M3 - Article

AN - SCOPUS:77955856339

VL - 59

SP - 66

EP - 74

JO - Russian Chemical Bulletin

JF - Russian Chemical Bulletin

SN - 1066-5285

IS - 1

M1 - 6

ER -

ID: 34424038