Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Anti-inflammatory and cell proliferative effect of the 1270 nm laser irradiation on the BALB/c nude mouse model involves activation of the cell antioxidant system. / Dolgova, Dinara; Abakumova, Tatiana; Gening, Tatiana и др.
в: Biomedical Optics Express, Том 10, № 8, 363565, 01.08.2019, стр. 4261-4275.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Anti-inflammatory and cell proliferative effect of the 1270 nm laser irradiation on the BALB/c nude mouse model involves activation of the cell antioxidant system
AU - Dolgova, Dinara
AU - Abakumova, Tatiana
AU - Gening, Tatiana
AU - Poludnyakova, Ludmila
AU - Zolotovskii, Igor
AU - Stoliarov, Dmitrii
AU - Fotiadi, Andrei
AU - Khokhlova, Anna
AU - Rafailov, Edik
AU - Sokolovski, Sergei
N1 - Publisher Copyright: © 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.
PY - 2019/8/1
Y1 - 2019/8/1
N2 - Recently, many interdisciplinary community researchers have focused their efforts on study of the low-level light irradiation effects (photobiomodulation, PBM) as a promising therapeutic technology. Among the priorities, a search of new wavelength ranges of laser radiation to enhance the laser prospects in treatment of autoimmune and cancer diseases commonly accompanied by disorders in the antioxidant system of the body. The laser wavelengths within 1265-1270 nm corresponds to the maximum oxygen absorption band. Therefore, PBM effects on a model organism within this spectrum range are of particular interest for preclinical research. Here, we report comprehensive biomolecular studies of the changes in the BALB/c nude mice skin after an exposure to the continuous laser radiation at the 1270 nm wavelength and energy densities of 0.12 and 1.2 J/cm2. Such regime induces both local and systemic PBM effects, presumably due to the short-term increase in ROS levels, which in turn activate the cell antioxidative system.
AB - Recently, many interdisciplinary community researchers have focused their efforts on study of the low-level light irradiation effects (photobiomodulation, PBM) as a promising therapeutic technology. Among the priorities, a search of new wavelength ranges of laser radiation to enhance the laser prospects in treatment of autoimmune and cancer diseases commonly accompanied by disorders in the antioxidant system of the body. The laser wavelengths within 1265-1270 nm corresponds to the maximum oxygen absorption band. Therefore, PBM effects on a model organism within this spectrum range are of particular interest for preclinical research. Here, we report comprehensive biomolecular studies of the changes in the BALB/c nude mice skin after an exposure to the continuous laser radiation at the 1270 nm wavelength and energy densities of 0.12 and 1.2 J/cm2. Such regime induces both local and systemic PBM effects, presumably due to the short-term increase in ROS levels, which in turn activate the cell antioxidative system.
KW - SINGLET OXYGEN
KW - MICRORNA EXPRESSION
KW - OXIDATIVE STRESS
KW - BREAST-CANCER
KW - TNF-ALPHA
KW - SKIN
KW - RADIATION
KW - THERAPY
KW - PHOTOTHERAPY
KW - MECHANISMS
UR - http://www.scopus.com/inward/record.url?scp=85071036775&partnerID=8YFLogxK
U2 - 10.1364/BOE.10.004261
DO - 10.1364/BOE.10.004261
M3 - Article
C2 - 31453009
AN - SCOPUS:85071036775
VL - 10
SP - 4261
EP - 4275
JO - Biomedical Optics Express
JF - Biomedical Optics Express
SN - 2156-7085
IS - 8
M1 - 363565
ER -
ID: 21347335