Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Analytical design of the human bronchial tree for healthy patients and patients with obstructive pulmonary diseases. / Medvedev, A. E.; Gafurova, P. S.
в: Mathematical Biology and Bioinformatics, Том 14, № 2, 01.02.2019, стр. 635-648.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Analytical design of the human bronchial tree for healthy patients and patients with obstructive pulmonary diseases
AU - Medvedev, A. E.
AU - Gafurova, P. S.
PY - 2019/2/1
Y1 - 2019/2/1
N2 - The study is aimed at the analytical design of the full human bronchial tree for healthy patients and patients with obstructive pulmonary diseases. Analytical formulas for design of the full bronchial tree are derived. All surfaces of the bronchial tree are matched with the second-order smoothness (there are no acute angles or ribs). The geometric characteristics of the human bronchial tree in the pathological case are modeled by a "starry" shape of the inner structure of the bronchus; the pathology degree is defined by two parameters: bronchus constriction level and degree of distortion of the cylindrical shape of the bronchus. Closed analytical formulas allow the human bronchial tree of an arbitrary complexity (up to alveoli) to be designed; moreover, the parametric dependences make it possible to specify any desirable degree of airway obstruction.
AB - The study is aimed at the analytical design of the full human bronchial tree for healthy patients and patients with obstructive pulmonary diseases. Analytical formulas for design of the full bronchial tree are derived. All surfaces of the bronchial tree are matched with the second-order smoothness (there are no acute angles or ribs). The geometric characteristics of the human bronchial tree in the pathological case are modeled by a "starry" shape of the inner structure of the bronchus; the pathology degree is defined by two parameters: bronchus constriction level and degree of distortion of the cylindrical shape of the bronchus. Closed analytical formulas allow the human bronchial tree of an arbitrary complexity (up to alveoli) to be designed; moreover, the parametric dependences make it possible to specify any desirable degree of airway obstruction.
KW - Bifurcation
KW - Bronchial tree
KW - Human lungs
KW - Respiratory system
KW - Simulation
UR - http://www.scopus.com/inward/record.url?scp=85083234231&partnerID=8YFLogxK
U2 - 10.17537/2019.14.635
DO - 10.17537/2019.14.635
M3 - Article
AN - SCOPUS:85083234231
VL - 14
SP - 635
EP - 648
JO - Mathematical Biology and Bioinformatics
JF - Mathematical Biology and Bioinformatics
SN - 1994-6538
IS - 2
ER -
ID: 24160739