Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
An Approach to the Synthesis of Cyclic Photocleavable RNA for Photoactivatable CRISPR/Cas9 System. / Ivanskaya, E. V.; Meschaninova, M. I.; Vorobyeva, M. A. и др.
в: Russian Journal of Bioorganic Chemistry, Том 50, № 5, 10.2024, стр. 1807-1821.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - An Approach to the Synthesis of Cyclic Photocleavable RNA for Photoactivatable CRISPR/Cas9 System
AU - Ivanskaya, E. V.
AU - Meschaninova, M. I.
AU - Vorobyeva, M. A.
AU - Zharkov, D. O.
AU - Novopashina, D. S.
N1 - This work was supported by the Russian Scientific Foundation (project no. 22-14-00294) and basic budget funding in the framework of the state assignment of the Institute of Chemical Biology and Fundamental Medicine SB RAS (2021–2024) no. 121031300042-1.
PY - 2024/10
Y1 - 2024/10
N2 - A new look at the nature of spatial development in Russia assumes structural shifts of economic activity in the latitudinal direction. The main questions posed in this regard in the article boil down to the following. How dynamic can and should the development of the eastern territories be? Is it enough that the pace of their development corresponds to all-Russian indicators, or is preferential growth considered appropriate? A specific task is to assess the investment conditions under which, in the long term until 2026, an increase in the share of the eastern regions in the country’s GRP is possible. It is shown that in the case of prolongation of the existing ratio of incremental capital intensity in the Asian part of the country and the Russian Federation as a whole, an increase in the share of the Asian part in the GRP of the Russian Federation requires unreasonably high investment costs. A good result should be considered the stabilization of this share by 2025, with an average accumulation rate during the forecast period in the Asian part of approximately 30%.
AB - A new look at the nature of spatial development in Russia assumes structural shifts of economic activity in the latitudinal direction. The main questions posed in this regard in the article boil down to the following. How dynamic can and should the development of the eastern territories be? Is it enough that the pace of their development corresponds to all-Russian indicators, or is preferential growth considered appropriate? A specific task is to assess the investment conditions under which, in the long term until 2026, an increase in the share of the eastern regions in the country’s GRP is possible. It is shown that in the case of prolongation of the existing ratio of incremental capital intensity in the Asian part of the country and the Russian Federation as a whole, an increase in the share of the Asian part in the GRP of the Russian Federation requires unreasonably high investment costs. A good result should be considered the stabilization of this share by 2025, with an average accumulation rate during the forecast period in the Asian part of approximately 30%.
KW - UV irradiation
KW - controllable CRISPR/Cas9 system
KW - cyclic RNA
KW - guide crRNA
KW - photocleavable linker
UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85206259820&origin=inward&txGid=79ab2cae47896c024f785c404f46c139
UR - https://www.mendeley.com/catalogue/4220b2d1-b5f4-3232-8258-99a06a592f4a/
U2 - 10.1134/S1068162024050327
DO - 10.1134/S1068162024050327
M3 - Article
VL - 50
SP - 1807
EP - 1821
JO - Russian Journal of Bioorganic Chemistry
JF - Russian Journal of Bioorganic Chemistry
SN - 1068-1620
IS - 5
ER -
ID: 60793736