Результаты исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › Рецензирование
A parameter identification problem for the mathematical model of HIV dynamics. / Kabanikhin, Sergey; Krivorotko, Olga; Yermolenko, Darya.
Proceedings - 2017 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2017. Institute of Electrical and Electronics Engineers Inc., 2017. стр. 82-86 8109842.Результаты исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › Рецензирование
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TY - GEN
T1 - A parameter identification problem for the mathematical model of HIV dynamics
AU - Kabanikhin, Sergey
AU - Krivorotko, Olga
AU - Yermolenko, Darya
PY - 2017/11/14
Y1 - 2017/11/14
N2 - In this paper, a problem of specifying HIV-infection parameters and immune response using additional measurements of the concentrations of the T-lymphocytes, the free virus, and the immune effectors at fixed times for a mathematical model of HIV dynamics is investigated numerically. The problem of specifying the parameters of the mathematical model (an inverse problem) is reduced to a problem of minimizing an objective function describing the deviation of the simulation results from the experimental data. A genetic algorithm for solving the least squares function minimization problem method is implemented and investigated. The results of a numerical solution of the inverse problem are analyzed.
AB - In this paper, a problem of specifying HIV-infection parameters and immune response using additional measurements of the concentrations of the T-lymphocytes, the free virus, and the immune effectors at fixed times for a mathematical model of HIV dynamics is investigated numerically. The problem of specifying the parameters of the mathematical model (an inverse problem) is reduced to a problem of minimizing an objective function describing the deviation of the simulation results from the experimental data. A genetic algorithm for solving the least squares function minimization problem method is implemented and investigated. The results of a numerical solution of the inverse problem are analyzed.
KW - Genetic algorithm
KW - Inverse problem
KW - Least square method
KW - Mathematical model of HIV dynamics
UR - http://www.scopus.com/inward/record.url?scp=85040507339&partnerID=8YFLogxK
U2 - 10.1109/SIBIRCON.2017.8109842
DO - 10.1109/SIBIRCON.2017.8109842
M3 - Conference contribution
AN - SCOPUS:85040507339
SP - 82
EP - 86
BT - Proceedings - 2017 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2017
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2017 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2017
Y2 - 18 September 2017 through 22 September 2017
ER -
ID: 9640833