TY - JOUR

T1 - A Novel High-Resolution Method for the Respiration Rate and Breathing Waveforms Remote Monitoring

AU - Vainer, Boris G.

PY - 2018/7/1

Y1 - 2018/7/1

N2 - A search for robust noninvasive methods permitting to discern the respiration subtle peculiarities in mammals is a topical issue. A novel approach called “sorption-enhanced infrared thermography” (SEIRT), helping to solve this problem, is described. Its benefits spring from the integration of the infrared thermography (IRT) and chemical physics (phase transition heat release/absorption) within a single method. The SEIRT opportunities were verified in the investigation of 42 humans, 49 rats and 4 minipigs whose breathing waveforms were revealed to the last detail. It is shown that the SEIRT-obtained breathing-conditioned temperature response may exceed 10 °C (!) even in small animals (rats) and that the SEIRT sensitivity is 4.5–250 times higher than that of the matched IRT-based techniques. The new method is validated by a comparison with that based on thorax breathing movement (TBM). It is shown that the SEIRT-determined breaths have a close correlation with those determined via TBM (r = + 1.000, p ≪ 0.05); this is also true for breathing intervals (r = + 0.9772, p ≪ 0.05). SEIRT opens up the way to a high-resolution noncontact quantitative evaluation of respiration rate and breathing waveforms in both humans and animals. It may become a cutting-edge technique in diagnostic medicine and biomedical research.

AB - A search for robust noninvasive methods permitting to discern the respiration subtle peculiarities in mammals is a topical issue. A novel approach called “sorption-enhanced infrared thermography” (SEIRT), helping to solve this problem, is described. Its benefits spring from the integration of the infrared thermography (IRT) and chemical physics (phase transition heat release/absorption) within a single method. The SEIRT opportunities were verified in the investigation of 42 humans, 49 rats and 4 minipigs whose breathing waveforms were revealed to the last detail. It is shown that the SEIRT-obtained breathing-conditioned temperature response may exceed 10 °C (!) even in small animals (rats) and that the SEIRT sensitivity is 4.5–250 times higher than that of the matched IRT-based techniques. The new method is validated by a comparison with that based on thorax breathing movement (TBM). It is shown that the SEIRT-determined breaths have a close correlation with those determined via TBM (r = + 1.000, p ≪ 0.05); this is also true for breathing intervals (r = + 0.9772, p ≪ 0.05). SEIRT opens up the way to a high-resolution noncontact quantitative evaluation of respiration rate and breathing waveforms in both humans and animals. It may become a cutting-edge technique in diagnostic medicine and biomedical research.

KW - Adsorption/desorption heat

KW - Animals

KW - Breathing sorption indicator

KW - Humans

KW - Infrared thermography

KW - Mammals

KW - INFRARED THERMOGRAPHY

KW - VASCULAR-RESPONSE

KW - PLETHYSMOGRAPHY

KW - AIRWAY-RESISTANCE

UR - http://www.scopus.com/inward/record.url?scp=85044930631&partnerID=8YFLogxK

U2 - 10.1007/s10439-018-2018-6

DO - 10.1007/s10439-018-2018-6

M3 - Article

C2 - 29619590

AN - SCOPUS:85044930631

VL - 46

SP - 960

EP - 971

JO - Annals of Biomedical Engineering

JF - Annals of Biomedical Engineering

SN - 0090-6964

IS - 7

ER -