Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
A facile approach to hybrid compounds containing a tricyclic diterpenoid and fluorine-substituted heterocycles. / Gromova, M. A.; Kharitonov, Yu V.; Politanskaya, L. V. и др.
в: Journal of Fluorine Chemistry, Том 236, 109554, 01.08.2020.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - A facile approach to hybrid compounds containing a tricyclic diterpenoid and fluorine-substituted heterocycles
AU - Gromova, M. A.
AU - Kharitonov, Yu V.
AU - Politanskaya, L. V.
AU - Tretyakov, E. V.
AU - Shults, E. E.
N1 - Publisher Copyright: © 2020 Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/8/1
Y1 - 2020/8/1
N2 - 2,3-Butadienes have become valuable building blocks in the synthesis of various heterocyclic compounds. The Pd-catalyzed cross-coupling and cyclization reaction of N-(2,3-butadienyl)carboxamide of isopimaric acid with fluorine-substituted 2-iodophenols proceeds with the formation of optically active fluorinated benzofuran and benzopyrane derivatives of isopimaric acid. This transformation opens a potential route to the synthesis of hybrid compounds containing a tricyclic diterpenoid moiety and several fluorinated benzoannelated heterocycles.
AB - 2,3-Butadienes have become valuable building blocks in the synthesis of various heterocyclic compounds. The Pd-catalyzed cross-coupling and cyclization reaction of N-(2,3-butadienyl)carboxamide of isopimaric acid with fluorine-substituted 2-iodophenols proceeds with the formation of optically active fluorinated benzofuran and benzopyrane derivatives of isopimaric acid. This transformation opens a potential route to the synthesis of hybrid compounds containing a tricyclic diterpenoid moiety and several fluorinated benzoannelated heterocycles.
KW - 2Н-chromenes
KW - Benzofurans
KW - Cross-coupling-cyclization
KW - Fluorinated heterocycles
KW - Isopimaric acid
KW - Terpenoid allene
KW - BIOACTIVITY
KW - ACID
KW - PHARMACEUTICALS
KW - CHROMENE
KW - 2H-chromenes
KW - BENZOFURANS
KW - DERIVATIVES
KW - EFFICIENT
UR - http://www.scopus.com/inward/record.url?scp=85085295681&partnerID=8YFLogxK
U2 - 10.1016/j.jfluchem.2020.109554
DO - 10.1016/j.jfluchem.2020.109554
M3 - Article
AN - SCOPUS:85085295681
VL - 236
JO - Journal of Fluorine Chemistry
JF - Journal of Fluorine Chemistry
SN - 0022-1139
M1 - 109554
ER -
ID: 24397851