What Tactics Should a Surgeon Choose to Treat a Black Extracerebral Tumor? A Case Report of Psammomatous Melanotic Schwannoma of the Meckel Cave and Literature Review. / Moisak, Galina I.; Matsko, Dmitry E.; Chernov, Sergey V. et al.
In: World Neurosurgery, Vol. 116, 01.08.2018, p. 337-342.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - What Tactics Should a Surgeon Choose to Treat a Black Extracerebral Tumor? A Case Report of Psammomatous Melanotic Schwannoma of the Meckel Cave and Literature Review
AU - Moisak, Galina I.
AU - Matsko, Dmitry E.
AU - Chernov, Sergey V.
AU - Dmitriev, Aleksandr B.
AU - Amelin, Mikhail E.
AU - Zhelbunova, Elena A.
AU - Chernov, Mikhail F.
AU - Rzaev, Jamil A.
N1 - Copyright © 2018 Elsevier Inc. All rights reserved.
PY - 2018/8/1
Y1 - 2018/8/1
N2 - Background: Neoplasms located in the Meckel cave account for 0.2%–0.5% of all intracranial tumors. This area is the site of many types of pathologic lesions, most often trigeminal nerve schwannomas and meningiomas. Melanin-containing tumors are rare in this area. These tumor types can be suspected if the magnetic resonance characteristics of a tumor has some differences in comparison with other types of central nervous system neoplasms. In fact, differential diagnosis of melanotic tumors is based mainly on the histopathologic criteria and immunohistochemical profile. This article presents a case report of melanotic schwannoma of the Meckel cave and a literature review of the problem. Case Description: A 23-year-old man underwent a 2-stage surgery for a dumbbell pigmented mass lesion located in the Meckel cave. No signs of recurrence were seen on follow-up magnetic resonance imaging (MRI) 3.5 years after the operation. Conclusions: Melanin-containing tumor can be suspected in the presence of radiologic characteristics, such as a hyperintense MRI signal on T1-weighted images and a hypointense signal on T2-weighted images. If a black extracerebral tumor is detected, the main course of surgical treatment is maximal excision despite it possibly being a malignant melanoma and the temptation to perform partial resection because of an unfavorable prognosis. Chemotherapy can be justified in the presence of an aggressive melanotic schwannoma.
AB - Background: Neoplasms located in the Meckel cave account for 0.2%–0.5% of all intracranial tumors. This area is the site of many types of pathologic lesions, most often trigeminal nerve schwannomas and meningiomas. Melanin-containing tumors are rare in this area. These tumor types can be suspected if the magnetic resonance characteristics of a tumor has some differences in comparison with other types of central nervous system neoplasms. In fact, differential diagnosis of melanotic tumors is based mainly on the histopathologic criteria and immunohistochemical profile. This article presents a case report of melanotic schwannoma of the Meckel cave and a literature review of the problem. Case Description: A 23-year-old man underwent a 2-stage surgery for a dumbbell pigmented mass lesion located in the Meckel cave. No signs of recurrence were seen on follow-up magnetic resonance imaging (MRI) 3.5 years after the operation. Conclusions: Melanin-containing tumor can be suspected in the presence of radiologic characteristics, such as a hyperintense MRI signal on T1-weighted images and a hypointense signal on T2-weighted images. If a black extracerebral tumor is detected, the main course of surgical treatment is maximal excision despite it possibly being a malignant melanoma and the temptation to perform partial resection because of an unfavorable prognosis. Chemotherapy can be justified in the presence of an aggressive melanotic schwannoma.
KW - Melanin-containing tumor
KW - Melanotic schwannoma
KW - Psammomatous schwannoma
KW - Tumor of Meckel cave
KW - DIAGNOSIS
KW - MANIFESTATION
KW - CARNEY COMPLEX
KW - LESIONS
KW - FEATURES
KW - CT
KW - CENTRAL-NERVOUS-SYSTEM
KW - PATIENT
KW - MENINGEAL MELANOCYTOMA
KW - Brain Neoplasms/diagnostic imaging
KW - Humans
KW - Male
KW - Young Adult
KW - Neurosurgical Procedures/methods
KW - Tomography Scanners, X-Ray Computed
KW - Melanoma-Specific Antigens/metabolism
KW - S100 Proteins/metabolism
KW - Melanoma/complications
KW - Ki-67 Antigen/metabolism
KW - Magnetic Resonance Imaging
KW - Neurilemmoma/complications
UR - http://www.scopus.com/inward/record.url?scp=85049007096&partnerID=8YFLogxK
U2 - 10.1016/j.wneu.2018.04.153
DO - 10.1016/j.wneu.2018.04.153
M3 - Article
C2 - 29715570
AN - SCOPUS:85049007096
VL - 116
SP - 337
EP - 342
JO - World Neurosurgery
JF - World Neurosurgery
SN - 1878-8750
ER -
ID: 14191790