Research output: Contribution to journal › Article › peer-review
Visualising the membrane viscosity of porcine eye lens cells using molecular rotors. / Sherin, Peter S.; López-Duarte, Ismael; Dent, Michael R. et al.
In: Chemical Science, Vol. 8, No. 5, 01.05.2017, p. 3523-3528.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Visualising the membrane viscosity of porcine eye lens cells using molecular rotors
AU - Sherin, Peter S.
AU - López-Duarte, Ismael
AU - Dent, Michael R.
AU - Kubánková, Markéta
AU - Vyšniauskas, Aurimas
AU - Bull, James A.
AU - Reshetnikova, Evdokiya S.
AU - Klymchenko, Andrey S.
AU - Tsentalovich, Yuri P.
AU - Kuimova, Marina K.
PY - 2017/5/1
Y1 - 2017/5/1
N2 - The plasma membranes of cells within the eye lens play an important role in metabolite transport within the avascular tissue of the lens, maintaining its transparency over the entire lifespan of an individual. Here we use viscosity-sensitive 'molecular rotors' to map the microscopic viscosity within these unusual cell membranes, establishing that they are characterised by an unprecedentedly high degree of lipid organisation.
AB - The plasma membranes of cells within the eye lens play an important role in metabolite transport within the avascular tissue of the lens, maintaining its transparency over the entire lifespan of an individual. Here we use viscosity-sensitive 'molecular rotors' to map the microscopic viscosity within these unusual cell membranes, establishing that they are characterised by an unprecedentedly high degree of lipid organisation.
KW - DIFFUSION
KW - DOMAINS
KW - FLUORESCENCE MICROSCOPY
KW - INNER MEMBRANE
KW - LIPID ORDER
KW - LIVE CELLS
KW - NUCLEAR CATARACT
KW - PLASMA-MEMBRANE
KW - PROBES
KW - SPORES
UR - http://www.scopus.com/inward/record.url?scp=85021659826&partnerID=8YFLogxK
U2 - 10.1039/c6sc05369f
DO - 10.1039/c6sc05369f
M3 - Article
C2 - 28580097
AN - SCOPUS:85021659826
VL - 8
SP - 3523
EP - 3528
JO - Chemical Science
JF - Chemical Science
SN - 2041-6520
IS - 5
ER -
ID: 10098392