Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments

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Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments. / Vernot, Benjamin; Zavala, Elena I.; Gómez-Olivencia, Asier et al.

In: Science, Vol. 372, No. 6542, 590, 07.05.2021.

Research output: Contribution to journal › Article › peer-review

Harvard

Vernot, B, Zavala, EI, Gómez-Olivencia, A, Jacobs, Z, Slon, V, Mafessoni, F, Romagné, F, Pearson, A, Petr, M, Sala, N, Pablos, A, Aranbur, A, De Castro, JMB, Carbonell, E, Li, B, Krajcarz, MT, Krivoshapkin, AI, Kolobova, KA, Kozlikin, MB, Shunkov, MV , Derevianko, AP, Viola, B, Grote, S, Essel, E, Herraéz, DL, Nagel, S, Nickel, B, Richter, J, Schmidt, A, Peter, B, Kelso, J, Roberts, RG, Arsuaga, JL & Meyer, M 2021, 'Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments', Science, vol. 372, no. 6542, 590. https://doi.org/10.1126/science.abf1667

APA

Vernot, B., Zavala, E. I., Gómez-Olivencia, A., Jacobs, Z., Slon, V., Mafessoni, F., Romagné, F., Pearson, A., Petr, M., Sala, N., Pablos, A., Aranbur, A., De Castro, J. M. B., Carbonell, E., Li, B., Krajcarz, M. T., Krivoshapkin, A. I., Kolobova, K. A., Kozlikin, M. B., ... Meyer, M. (2021). Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments. Science, 372(6542), [590]. https://doi.org/10.1126/science.abf1667

Vancouver

Vernot B, Zavala EI, Gómez-Olivencia A, Jacobs Z, Slon V, Mafessoni F et al. Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments. Science. 2021 May 7;372(6542):590. doi: 10.1126/science.abf1667

Author

Vernot, Benjamin ; Zavala, Elena I. ; Gómez-Olivencia, Asier et al. / Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments. In: Science. 2021 ; Vol. 372, No. 6542.

BibTeX

@article{3e6ab99ad0e94c678bf6beca9418c4b4,

title = "Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments",

abstract = "Bones and teeth are important sources of Pleistocene hominin DNA, but are rarely recovered at archaeological sites. Mitochondrial DNA (mtDNA) has been retrieved from cave sediments but provides limited value for studying population relationships. We therefore developed methods for the enrichment and analysis of nuclear DNA from sediments and applied them to cave deposits in western Europe and southern Siberia dated to between 200,000 and 50,000 years ago. We detected a population replacement in northern Spain about 100,000 years ago, which was accompanied by a turnover of mtDNA. We also identified two radiation events in Neanderthal history during the early part of the Late Pleistocene. Our work lays the ground for studying the population history of ancient hominins from trace amounts of nuclear DNA in sediments.",

keywords = "Animals, Caves/chemistry, Cell Nucleus/genetics, DNA, Mitochondrial/analysis, Geologic Sediments/chemistry, Neanderthals/classification, Phylogeny, Population/genetics, Sequence Analysis, DNA, Siberia, Spain",

author = "Benjamin Vernot and Zavala, {Elena I.} and Asier G{\'o}mez-Olivencia and Zenobia Jacobs and Viviane Slon and Fabrizio Mafessoni and Fr{\'e}d{\'e}ric Romagn{\'e} and Alice Pearson and Martin Petr and Nohemi Sala and Adri{\'a}n Pablos and Arantza Aranbur and {De Castro}, {Jos{\'e} Mari{\'a} Berm{\'u}dez} and Eudald Carbonell and Bo Li and Krajcarz, {MacIej T.} and Krivoshapkin, {Andrey I.} and Kolobova, {Kseniya A.} and Kozlikin, {Maxim B.} and Shunkov, {Michael V.} and Derevianko, {Anatoly P.} and Bence Viola and Steffi Grote and Elena Essel and Herra{\'e}z, {David L{\'o}pez} and Sarah Nagel and Birgit Nickel and Julia Richter and Anna Schmidt and Benjamin Peter and Janet Kelso and Roberts, {Richard G.} and Arsuaga, {Juan Luis} and Matthias Meyer",

year = "2021",

month = may,

day = "7",

doi = "10.1126/science.abf1667",

language = "English",

volume = "372",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "6542",

}

RIS

TY - JOUR

T1 - Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments

AU - Vernot, Benjamin

AU - Zavala, Elena I.

AU - Gómez-Olivencia, Asier

AU - Jacobs, Zenobia

AU - Slon, Viviane

AU - Mafessoni, Fabrizio

AU - Romagné, Frédéric

AU - Pearson, Alice

AU - Petr, Martin

AU - Sala, Nohemi

AU - Pablos, Adrián

AU - Aranbur, Arantza

AU - De Castro, José Mariá Bermúdez

AU - Carbonell, Eudald

AU - Li, Bo

AU - Krajcarz, MacIej T.

AU - Krivoshapkin, Andrey I.

AU - Kolobova, Kseniya A.

AU - Kozlikin, Maxim B.

AU - Shunkov, Michael V.

AU - Derevianko, Anatoly P.

AU - Viola, Bence

AU - Grote, Steffi

AU - Essel, Elena

AU - Herraéz, David López

AU - Nagel, Sarah

AU - Nickel, Birgit

AU - Richter, Julia

AU - Schmidt, Anna

AU - Peter, Benjamin

AU - Kelso, Janet

AU - Roberts, Richard G.

AU - Arsuaga, Juan Luis

AU - Meyer, Matthias

PY - 2021/5/7

Y1 - 2021/5/7

N2 - Bones and teeth are important sources of Pleistocene hominin DNA, but are rarely recovered at archaeological sites. Mitochondrial DNA (mtDNA) has been retrieved from cave sediments but provides limited value for studying population relationships. We therefore developed methods for the enrichment and analysis of nuclear DNA from sediments and applied them to cave deposits in western Europe and southern Siberia dated to between 200,000 and 50,000 years ago. We detected a population replacement in northern Spain about 100,000 years ago, which was accompanied by a turnover of mtDNA. We also identified two radiation events in Neanderthal history during the early part of the Late Pleistocene. Our work lays the ground for studying the population history of ancient hominins from trace amounts of nuclear DNA in sediments.

AB - Bones and teeth are important sources of Pleistocene hominin DNA, but are rarely recovered at archaeological sites. Mitochondrial DNA (mtDNA) has been retrieved from cave sediments but provides limited value for studying population relationships. We therefore developed methods for the enrichment and analysis of nuclear DNA from sediments and applied them to cave deposits in western Europe and southern Siberia dated to between 200,000 and 50,000 years ago. We detected a population replacement in northern Spain about 100,000 years ago, which was accompanied by a turnover of mtDNA. We also identified two radiation events in Neanderthal history during the early part of the Late Pleistocene. Our work lays the ground for studying the population history of ancient hominins from trace amounts of nuclear DNA in sediments.

KW - Animals

KW - Caves/chemistry

KW - Cell Nucleus/genetics

KW - DNA, Mitochondrial/analysis

KW - Geologic Sediments/chemistry

KW - Neanderthals/classification

KW - Phylogeny

KW - Population/genetics

KW - Sequence Analysis, DNA

KW - Siberia

KW - Spain

UR - http://www.scopus.com/inward/record.url?scp=85105400983&partnerID=8YFLogxK

U2 - 10.1126/science.abf1667

DO - 10.1126/science.abf1667

M3 - Article

C2 - 33858989

AN - SCOPUS:85105400983

VL - 372

JO - Science

JF - Science

SN - 0036-8075

IS - 6542

M1 - 590

ER -

ID: 28555876