Research output: Contribution to journal › Article › peer-review
Ultrasonography patterns of atopic dermatitis in children. / Sorokina, Elena; Mikailova, Daria; Krakhaleva, Julia et al.
In: Skin Research and Technology, Vol. 26, No. 4, 01.07.2020, p. 482-488.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Ultrasonography patterns of atopic dermatitis in children
AU - Sorokina, Elena
AU - Mikailova, Daria
AU - Krakhaleva, Julia
AU - Krinitsyna, Julia
AU - Yakubovich, Andrey
AU - Sergeeva, Irina
N1 - © 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - Background: Atopic dermatitis (AD) is one of the most common allergic diseases in children. The aim of the study was to evaluate the ultrasound picture of lesional and non-lesional skin in children with AD. Materials and Methods: The study included a group of children with AD and a control group. Inclusion criteria were as follows: age 0-8 years and clinical diagnosis of AD. An ultrasound scanner with a 75 MHz transducer probe was used to produce B-mode skin images in lesions and non-lesional skin. The thickness and the echogenicity of epidermis, dermis, and subepidermal low-echogenic band (SLEB) were measured, and the ratio coefficient per body site was calculated. Results: Ultrasonography of non-lesional skin in children with AD showed uneven epidermis contour, a tendency to increased epidermis and decreased dermis thickness, and the SLEB was observed in 77% of cases. In lesions, there was an increased thickness and a decreased echogenicity of epidermis and dermis, and epidermis had irregular contours in most cases. The SLEB was in all lesions, showing greater thickness and lower echogenicity compared with non-lesional skin. Conclusion: HF-USG of the skin allows visualizing the epidermal barrier disruption and inflammation in dermis in children with AD on the entire surface of the skin.
AB - Background: Atopic dermatitis (AD) is one of the most common allergic diseases in children. The aim of the study was to evaluate the ultrasound picture of lesional and non-lesional skin in children with AD. Materials and Methods: The study included a group of children with AD and a control group. Inclusion criteria were as follows: age 0-8 years and clinical diagnosis of AD. An ultrasound scanner with a 75 MHz transducer probe was used to produce B-mode skin images in lesions and non-lesional skin. The thickness and the echogenicity of epidermis, dermis, and subepidermal low-echogenic band (SLEB) were measured, and the ratio coefficient per body site was calculated. Results: Ultrasonography of non-lesional skin in children with AD showed uneven epidermis contour, a tendency to increased epidermis and decreased dermis thickness, and the SLEB was observed in 77% of cases. In lesions, there was an increased thickness and a decreased echogenicity of epidermis and dermis, and epidermis had irregular contours in most cases. The SLEB was in all lesions, showing greater thickness and lower echogenicity compared with non-lesional skin. Conclusion: HF-USG of the skin allows visualizing the epidermal barrier disruption and inflammation in dermis in children with AD on the entire surface of the skin.
KW - atopic dermatitis
KW - children
KW - high-frequency ultrasound
KW - subepidermal low-echogenic band
UR - http://www.scopus.com/inward/record.url?scp=85078638479&partnerID=8YFLogxK
U2 - 10.1111/srt.12839
DO - 10.1111/srt.12839
M3 - Article
C2 - 31930616
AN - SCOPUS:85078638479
VL - 26
SP - 482
EP - 488
JO - Skin Research and Technology
JF - Skin Research and Technology
SN - 0909-752X
IS - 4
ER -
ID: 23257773