Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review
Theoretical Substantiation for the Original Technique of Photodynamic Fractional Laser Photothermolysis (PFLP) for Dermatology, based on Intradermal Transport of Photosensibilisers. / Nikonov, Sergey; Chernopyatov, Danila; Shumkov, Oleg et al.
SIBIRCON 2019 - International Multi-Conference on Engineering, Computer and Information Sciences, Proceedings. Institute of Electrical and Electronics Engineers Inc., 2019. p. 1007-1010 8958204 (SIBIRCON 2019 - International Multi-Conference on Engineering, Computer and Information Sciences, Proceedings).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review
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TY - GEN
T1 - Theoretical Substantiation for the Original Technique of Photodynamic Fractional Laser Photothermolysis (PFLP) for Dermatology, based on Intradermal Transport of Photosensibilisers
AU - Nikonov, Sergey
AU - Chernopyatov, Danila
AU - Shumkov, Oleg
AU - Soluyanov, Mikhail
AU - Smagin, Mikhail
N1 - Publisher Copyright: © 2019 IEEE. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2019/10
Y1 - 2019/10
N2 - This review demonstrates the progress, current status and problems of photodynamic therapy and laser photothermolysis for various skin diseases and rejuvenation. These new minimally invasive technologies are detailed from the points of view of their advantages and disadvantages. Particular attention is paid to complications, associated with prolonged dermal phototoxicity after intravenous photosensibilisation and insufficient intradermal penetration of photosensibilisers after local application to skin. Finding a compromise between phototoxicity and insufficiency of local photosensibilisation we've developed a technical approach employed to overcome limitations associated with targeted delivery of photosensibilisers into deep dermal layers. Intradermal delivery of photosensibilisers through so-called microthermal zones or dermal micropores, formed by focused pulse-periodic radiation of fiber laser, previously never used for photodynamic therapy of dermal disorders.
AB - This review demonstrates the progress, current status and problems of photodynamic therapy and laser photothermolysis for various skin diseases and rejuvenation. These new minimally invasive technologies are detailed from the points of view of their advantages and disadvantages. Particular attention is paid to complications, associated with prolonged dermal phototoxicity after intravenous photosensibilisation and insufficient intradermal penetration of photosensibilisers after local application to skin. Finding a compromise between phototoxicity and insufficiency of local photosensibilisation we've developed a technical approach employed to overcome limitations associated with targeted delivery of photosensibilisers into deep dermal layers. Intradermal delivery of photosensibilisers through so-called microthermal zones or dermal micropores, formed by focused pulse-periodic radiation of fiber laser, previously never used for photodynamic therapy of dermal disorders.
KW - drug delivery
KW - intradermal transport. skin diseases
KW - photodynamic therapy
KW - photothermolysis
KW - rejuvenation
UR - http://www.scopus.com/inward/record.url?scp=85079038555&partnerID=8YFLogxK
U2 - 10.1109/SIBIRCON48586.2019.8958204
DO - 10.1109/SIBIRCON48586.2019.8958204
M3 - Conference contribution
T3 - SIBIRCON 2019 - International Multi-Conference on Engineering, Computer and Information Sciences, Proceedings
SP - 1007
EP - 1010
BT - SIBIRCON 2019 - International Multi-Conference on Engineering, Computer and Information Sciences, Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2019 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2019
Y2 - 21 October 2019 through 27 October 2019
ER -
ID: 23427631