Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review
The tendency to hypercoagulation in the perioperative period of uterine artery embolization. / Irina, Siutkina; Dmitriy, Khabarov; Alexandr, Smagin et al.
Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020. Institute of Electrical and Electronics Engineers Inc., 2020. p. 265-268 9214699 (Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review
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TY - GEN
T1 - The tendency to hypercoagulation in the perioperative period of uterine artery embolization
AU - Irina, Siutkina
AU - Dmitriy, Khabarov
AU - Alexandr, Smagin
AU - Pavel, Bulychev
AU - Alexander, Demura
AU - Alisa, Inyoshina
N1 - Publisher Copyright: © 2020 IEEE. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/7
Y1 - 2020/7
N2 - Purpose of the study: to assess the dynamics of changes in the blood coagulation system in the perioperative period during uterine artery embolization (UAE) based on monitoring of hemostasis system's indicators, including TEG, and the tendency (or its absence) to thrombosis. The study included 37 patients with EMA, who in the course of preoperative examination excluded the contributing risk factors for thromboembolic complications. In the perioperative period, dynamic monitoring of coagulogram and thromboelastography was performed. One day after the UAE, the patients showed a tendency to hypercoagulation according to the TEG data (a decrease in the R, K time indices and an increase in the a-angle, MA value) and fibrinolysis activation (increased LY 30 index). At the same time, in the study of coagulogram indices, an increased level of hypercoagulation markers (fibrinogen, D-dimer, SFMC), Prothrombin index and a decreased APTT were revealed. Findings indicate, in general, an increased risk of VTE complications in the postoperative period after UAE. The revealed features of changes in hemostasis parameters in patients after UAE indicate the need for continuous monitoring of the hemostasis system and the development of effective measures for the prevention of VTE complication.
AB - Purpose of the study: to assess the dynamics of changes in the blood coagulation system in the perioperative period during uterine artery embolization (UAE) based on monitoring of hemostasis system's indicators, including TEG, and the tendency (or its absence) to thrombosis. The study included 37 patients with EMA, who in the course of preoperative examination excluded the contributing risk factors for thromboembolic complications. In the perioperative period, dynamic monitoring of coagulogram and thromboelastography was performed. One day after the UAE, the patients showed a tendency to hypercoagulation according to the TEG data (a decrease in the R, K time indices and an increase in the a-angle, MA value) and fibrinolysis activation (increased LY 30 index). At the same time, in the study of coagulogram indices, an increased level of hypercoagulation markers (fibrinogen, D-dimer, SFMC), Prothrombin index and a decreased APTT were revealed. Findings indicate, in general, an increased risk of VTE complications in the postoperative period after UAE. The revealed features of changes in hemostasis parameters in patients after UAE indicate the need for continuous monitoring of the hemostasis system and the development of effective measures for the prevention of VTE complication.
KW - hemostasis
KW - thromboelastography
KW - thromboembolic complications
KW - uterine artery embolization
UR - http://www.scopus.com/inward/record.url?scp=85094812862&partnerID=8YFLogxK
UR - https://elibrary.ru/item.asp?id=45205997
U2 - 10.1109/CSGB51356.2020.9214699
DO - 10.1109/CSGB51356.2020.9214699
M3 - Conference contribution
AN - SCOPUS:85094812862
T3 - Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020
SP - 265
EP - 268
BT - Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020
Y2 - 6 July 2020 through 10 July 2020
ER -
ID: 26007102