The mitochondrial genome of a freshwater pelagic amphipod Macrohectopus branickii is among the longest in Metazoa

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The mitochondrial genome of a freshwater pelagic amphipod Macrohectopus branickii is among the longest in Metazoa. / Romanova, Elena V.; Bukin, Yurij S.; Mikhailov, Kirill V. et al.

In: Genes, Vol. 12, No. 12, 2030, 12.2021.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{0d7bcbdd167647e58cb8be733407e02a,

title = "The mitochondrial genome of a freshwater pelagic amphipod Macrohectopus branickii is among the longest in Metazoa",

abstract = "There are more than 350 species of amphipods (Crustacea) in Lake Baikal, which have emerged predominantly through the course of endemic radiation. This group represents a remarkable model for studying various aspects of evolution, one of which is the evolution of mitochondrial (mt) genome architectures. We sequenced and assembled the mt genome of a pelagic Baikalian amphipod species Macrohectopus branickii. The mt genome is revealed to have an extraordinary length (42,256 bp), deviating significantly from the genomes of other amphipod species and the majority of animals. The mt genome of M. branickii has a unique gene order within amphipods, duplications of the four tRNA genes and Cox2, and a long non-coding region, that makes up about two thirds of the genome{\textquoteright}s size. The extension of the mt genome was most likely caused by multiple duplications and inversions of regions harboring ribosomal RNA genes. In this study, we analyzed the patterns of mt genome length changes in amphipods and other animal phyla. Through a statistical analysis, we demonstrated that the variability in the mt genome length may be a characteristic of certain phyla and is primarily conferred by expansions of non-coding regions.",

keywords = "Amphipods, Direct and inverted repeats, Gene duplications, Lake Baikal, Long mitochondrial genomes, Non-coding regions",

author = "Romanova, {Elena V.} and Bukin, {Yurij S.} and Mikhailov, {Kirill V.} and Logacheva, {Maria D.} and Aleoshin, {Vladimir V.} and Sherbakov, {Dmitry Y.}",

note = "Funding Information: Funding: This work was supported by the Ministry of Science and Higher Education of Russian Federation; progect 0279-2021-0010 (121032300196-8). Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = dec,

doi = "10.3390/genes12122030",

language = "English",

volume = "12",

journal = "Genes",

issn = "2073-4425",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "12",

}

RIS

TY - JOUR

T1 - The mitochondrial genome of a freshwater pelagic amphipod Macrohectopus branickii is among the longest in Metazoa

AU - Romanova, Elena V.

AU - Bukin, Yurij S.

AU - Mikhailov, Kirill V.

AU - Logacheva, Maria D.

AU - Aleoshin, Vladimir V.

AU - Sherbakov, Dmitry Y.

N1 - Funding Information: Funding: This work was supported by the Ministry of Science and Higher Education of Russian Federation; progect 0279-2021-0010 (121032300196-8). Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021/12

Y1 - 2021/12

N2 - There are more than 350 species of amphipods (Crustacea) in Lake Baikal, which have emerged predominantly through the course of endemic radiation. This group represents a remarkable model for studying various aspects of evolution, one of which is the evolution of mitochondrial (mt) genome architectures. We sequenced and assembled the mt genome of a pelagic Baikalian amphipod species Macrohectopus branickii. The mt genome is revealed to have an extraordinary length (42,256 bp), deviating significantly from the genomes of other amphipod species and the majority of animals. The mt genome of M. branickii has a unique gene order within amphipods, duplications of the four tRNA genes and Cox2, and a long non-coding region, that makes up about two thirds of the genome’s size. The extension of the mt genome was most likely caused by multiple duplications and inversions of regions harboring ribosomal RNA genes. In this study, we analyzed the patterns of mt genome length changes in amphipods and other animal phyla. Through a statistical analysis, we demonstrated that the variability in the mt genome length may be a characteristic of certain phyla and is primarily conferred by expansions of non-coding regions.

AB - There are more than 350 species of amphipods (Crustacea) in Lake Baikal, which have emerged predominantly through the course of endemic radiation. This group represents a remarkable model for studying various aspects of evolution, one of which is the evolution of mitochondrial (mt) genome architectures. We sequenced and assembled the mt genome of a pelagic Baikalian amphipod species Macrohectopus branickii. The mt genome is revealed to have an extraordinary length (42,256 bp), deviating significantly from the genomes of other amphipod species and the majority of animals. The mt genome of M. branickii has a unique gene order within amphipods, duplications of the four tRNA genes and Cox2, and a long non-coding region, that makes up about two thirds of the genome’s size. The extension of the mt genome was most likely caused by multiple duplications and inversions of regions harboring ribosomal RNA genes. In this study, we analyzed the patterns of mt genome length changes in amphipods and other animal phyla. Through a statistical analysis, we demonstrated that the variability in the mt genome length may be a characteristic of certain phyla and is primarily conferred by expansions of non-coding regions.

KW - Amphipods

KW - Direct and inverted repeats

KW - Gene duplications

KW - Lake Baikal

KW - Long mitochondrial genomes

KW - Non-coding regions

UR - http://www.scopus.com/inward/record.url?scp=85121576347&partnerID=8YFLogxK

U2 - 10.3390/genes12122030

DO - 10.3390/genes12122030

M3 - Article

C2 - 34946978

AN - SCOPUS:85121576347

VL - 12

JO - Genes

JF - Genes

SN - 2073-4425

IS - 12

M1 - 2030

ER -

ID: 35261662