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The genetic constituent of varicose vein pathogenesis as a key for future treatment option development. / Smetanina, Mariya A.; Shevela, Andrey I.; Gavrilov, Konstantin A. et al.

In: Vessel Plus, Vol. 5, 19, 2021.

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@article{b6523fbbf0bd4aaf92c4309413de81dd,
title = "The genetic constituent of varicose vein pathogenesis as a key for future treatment option development",
abstract = "This perspective focuses primarily on the fundamental part of phlebology, where most attention is paid to the genetic aspects of the pathogenesis of varicose vein disease and where the main breakthrough advances in this area of research are discussed. We propose a direction for further actions to replenish molecular genetic knowledge about the main drivers of pathological processes in varicose vein disease and to complete the creation of an entire picture of pathogenesis, which, in turn, may serve as a key for the development of treatment options in the future in order to translate research evidence into clinical practice.",
keywords = "Epigenetics, Genetics, Pathogenesis, Targets, Varicose veins",
author = "Smetanina, {Mariya A.} and Shevela, {Andrey I.} and Gavrilov, {Konstantin A.} and Filipenko, {Maxim L.}",
note = "Funding Information: The authors are grateful to the native English speakers Holly Jacob (Texas A&M University, USA) and Christine Tierney (Houston Community College, USA) for grammar checking assistance and thorough text revision. This work was supported by the Program of Fundamental Scientific Research of the Russian Federation (PFSR RF) “Fundamental Basics of Health Preservation” (No. 121031300045-2). Publisher Copyright: {\textcopyright} The Author(s) 2021.",
year = "2021",
doi = "10.20517/2574-1209.2021.17",
language = "English",
volume = "5",
journal = "Vessel Plus",
issn = "2574-1209",
publisher = "OAE Publishing Inc.",

}

RIS

TY - JOUR

T1 - The genetic constituent of varicose vein pathogenesis as a key for future treatment option development

AU - Smetanina, Mariya A.

AU - Shevela, Andrey I.

AU - Gavrilov, Konstantin A.

AU - Filipenko, Maxim L.

N1 - Funding Information: The authors are grateful to the native English speakers Holly Jacob (Texas A&M University, USA) and Christine Tierney (Houston Community College, USA) for grammar checking assistance and thorough text revision. This work was supported by the Program of Fundamental Scientific Research of the Russian Federation (PFSR RF) “Fundamental Basics of Health Preservation” (No. 121031300045-2). Publisher Copyright: © The Author(s) 2021.

PY - 2021

Y1 - 2021

N2 - This perspective focuses primarily on the fundamental part of phlebology, where most attention is paid to the genetic aspects of the pathogenesis of varicose vein disease and where the main breakthrough advances in this area of research are discussed. We propose a direction for further actions to replenish molecular genetic knowledge about the main drivers of pathological processes in varicose vein disease and to complete the creation of an entire picture of pathogenesis, which, in turn, may serve as a key for the development of treatment options in the future in order to translate research evidence into clinical practice.

AB - This perspective focuses primarily on the fundamental part of phlebology, where most attention is paid to the genetic aspects of the pathogenesis of varicose vein disease and where the main breakthrough advances in this area of research are discussed. We propose a direction for further actions to replenish molecular genetic knowledge about the main drivers of pathological processes in varicose vein disease and to complete the creation of an entire picture of pathogenesis, which, in turn, may serve as a key for the development of treatment options in the future in order to translate research evidence into clinical practice.

KW - Epigenetics

KW - Genetics

KW - Pathogenesis

KW - Targets

KW - Varicose veins

UR - http://www.scopus.com/inward/record.url?scp=85114077410&partnerID=8YFLogxK

UR - https://www.elibrary.ru/item.asp?id=47508009

UR - https://www.mendeley.com/catalogue/ff52257a-7d78-3017-9b2a-ec46a5d970ad/

U2 - 10.20517/2574-1209.2021.17

DO - 10.20517/2574-1209.2021.17

M3 - Review article

AN - SCOPUS:85114077410

VL - 5

JO - Vessel Plus

JF - Vessel Plus

SN - 2574-1209

M1 - 19

ER -

ID: 36433519