The dual role of methylglyoxal in plant stress response and regulation of DJ-1 protein

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The dual role of methylglyoxal in plant stress response and regulation of DJ-1 protein. / Sun, Yutong; Chen, Sixue; Grin, Inga R. et al.

In: Physiologia Plantarum, Vol. 176, No. 6, e14608, 11.2024.

Research output: Contribution to journal › Review article › peer-review

BibTeX

@article{1abb8c89bf1349678c1d91e2822ca54b,

title = "The dual role of methylglyoxal in plant stress response and regulation of DJ-1 protein",

abstract = "Methylglyoxal (MG) is a highly reactive metabolic intermediate that plays important roles in plant salt stress response. This review explores the sources of MG in plants, how salt stress promotes MG production, and the dual role of MG under salt stress conditions. Both the positive role of low concentrations of MG as a signalling molecule and the toxic effects of high concentrations of MG in plant response to salt stress are discussed. The MG detoxification pathways, especially the glyoxalase system, are described in detail. Special attention is given to the novel role of the DJ-1 protein in the glyoxalase system as glyoxalase III to remove MG, and as a deglycase to decrease glycation damage caused by MG on DNA, proteins, and other biomolecules. This review aims to provide readers with comprehensive perspectives on the functions of MG in plant salt stress response, the roles of the DJ-1 protein in MG detoxification and repair of glycation-damaged molecules, as well as the broader functional implications of MG in plant salt stress tolerance. New perspectives on maintaining plant genome stability, breeding for salt-tolerant crop varieties, and improving crop quality are discussed.",

keywords = "Pyruvaldehyde/metabolism, Protein Deglycase DJ-1/metabolism, Salt Stress/physiology, Plant Proteins/metabolism, Plants/metabolism, Stress, Physiological, Lactoylglutathione Lyase/metabolism, Gene Expression Regulation, Plant",

author = "Yutong Sun and Sixue Chen and Grin, {Inga R.} and Zharkov, {Dmitry O.} and Bing Yu and Haiying Li",

note = "This research was funded by InternationalCooperation and Exchange of the NationalScience. Foundation of China Project(32261133530) and the National ScienceFoundation of China Project (32072122) andthe Russian Science Foundation(23-44-00050), Grant/Award Numbers:23-44-00050, 32072122, 32261133530",

year = "2024",

month = nov,

doi = "10.1111/ppl.14608",

language = "English",

volume = "176",

journal = "Physiologia Plantarum",

issn = "0031-9317",

publisher = "Wiley-Blackwell",

number = "6",

}

RIS

TY - JOUR

T1 - The dual role of methylglyoxal in plant stress response and regulation of DJ-1 protein

AU - Sun, Yutong

AU - Chen, Sixue

AU - Grin, Inga R.

AU - Zharkov, Dmitry O.

AU - Yu, Bing

AU - Li, Haiying

N1 - This research was funded by InternationalCooperation and Exchange of the NationalScience. Foundation of China Project(32261133530) and the National ScienceFoundation of China Project (32072122) andthe Russian Science Foundation(23-44-00050), Grant/Award Numbers:23-44-00050, 32072122, 32261133530

PY - 2024/11

Y1 - 2024/11

N2 - Methylglyoxal (MG) is a highly reactive metabolic intermediate that plays important roles in plant salt stress response. This review explores the sources of MG in plants, how salt stress promotes MG production, and the dual role of MG under salt stress conditions. Both the positive role of low concentrations of MG as a signalling molecule and the toxic effects of high concentrations of MG in plant response to salt stress are discussed. The MG detoxification pathways, especially the glyoxalase system, are described in detail. Special attention is given to the novel role of the DJ-1 protein in the glyoxalase system as glyoxalase III to remove MG, and as a deglycase to decrease glycation damage caused by MG on DNA, proteins, and other biomolecules. This review aims to provide readers with comprehensive perspectives on the functions of MG in plant salt stress response, the roles of the DJ-1 protein in MG detoxification and repair of glycation-damaged molecules, as well as the broader functional implications of MG in plant salt stress tolerance. New perspectives on maintaining plant genome stability, breeding for salt-tolerant crop varieties, and improving crop quality are discussed.

AB - Methylglyoxal (MG) is a highly reactive metabolic intermediate that plays important roles in plant salt stress response. This review explores the sources of MG in plants, how salt stress promotes MG production, and the dual role of MG under salt stress conditions. Both the positive role of low concentrations of MG as a signalling molecule and the toxic effects of high concentrations of MG in plant response to salt stress are discussed. The MG detoxification pathways, especially the glyoxalase system, are described in detail. Special attention is given to the novel role of the DJ-1 protein in the glyoxalase system as glyoxalase III to remove MG, and as a deglycase to decrease glycation damage caused by MG on DNA, proteins, and other biomolecules. This review aims to provide readers with comprehensive perspectives on the functions of MG in plant salt stress response, the roles of the DJ-1 protein in MG detoxification and repair of glycation-damaged molecules, as well as the broader functional implications of MG in plant salt stress tolerance. New perspectives on maintaining plant genome stability, breeding for salt-tolerant crop varieties, and improving crop quality are discussed.

KW - Pyruvaldehyde/metabolism

KW - Protein Deglycase DJ-1/metabolism

KW - Salt Stress/physiology

KW - Plant Proteins/metabolism

KW - Plants/metabolism

KW - Stress, Physiological

KW - Lactoylglutathione Lyase/metabolism

KW - Gene Expression Regulation, Plant

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85208444949&origin=inward&txGid=a991817a2503710c3fb6cc9e3bb8f67a

UR - https://www.mendeley.com/catalogue/816b35dc-7feb-310f-8ba2-4fa34005fa82/

U2 - 10.1111/ppl.14608

DO - 10.1111/ppl.14608

M3 - Review article

C2 - 39508129

VL - 176

JO - Physiologia Plantarum

JF - Physiologia Plantarum

SN - 0031-9317

IS - 6

M1 - e14608

ER -

ID: 60835455