TAD border deletion at the Kit locus causes tissue-specific ectopic activation of a neighboring gene

Animals, Proto-Oncogene Proteins c-kit/genetics, Mice, Mast Cells/metabolism, Melanocytes/metabolism, Fibroblasts/metabolism, Chromatin/metabolism, Vascular Endothelial Growth Factor Receptor-2/genetics, Promoter Regions, Genetic/genetics, Enhancer Elements, Genetic/genetics, Receptor, Platelet-Derived Growth Factor alpha/genetics, Epigenesis, Genetic, Genetic Loci, Mice, Inbred C57BL, Organ Specificity/genetics, Gene Editing, Ectopic Gene Expression, Male

ID: 60383786