Synthesis of Fluorinated Octahydro-2H-Chromenes in the Presence of the BF3·Et2O–H2O Catalytic System. / Il’ina, Irina V.; Patrusheva, Oksana S.; Korchagina, Dina V. et al.
In: Chemistry of Heterocyclic Compounds, Vol. 56, No. 7, 01.07.2020, p. 867-874.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Synthesis of Fluorinated Octahydro-2H-Chromenes in the Presence of the BF3·Et2O–H2O Catalytic System
AU - Il’ina, Irina V.
AU - Patrusheva, Oksana S.
AU - Korchagina, Dina V.
AU - Volcho, Konstantin P.
AU - Salakhutdinov, Nariman F.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - The synthesis of fluorinated octahydro-2H-chromene was carried out using the Prins reaction between the monoterpenoid (–)-isopulegol and carbonyl compounds in the presence of the BF3·Et2O–H2O system, which acts as both an acid catalyst and a fluorine source. The use of the readily available and easy-to-use BF3·Et2O reagent makes this method of obtaining fluorine derivatives simple and practical.
AB - The synthesis of fluorinated octahydro-2H-chromene was carried out using the Prins reaction between the monoterpenoid (–)-isopulegol and carbonyl compounds in the presence of the BF3·Et2O–H2O system, which acts as both an acid catalyst and a fluorine source. The use of the readily available and easy-to-use BF3·Et2O reagent makes this method of obtaining fluorine derivatives simple and practical.
KW - acid catalysts
KW - boron trifluoride etherate
KW - chromene
KW - isopulegol
KW - monoterpenes
KW - organofluorine compounds
KW - Prins reaction
KW - REAGENT
KW - ACID
KW - TETRAHYDROPYRANS
KW - ISOPULEGOL
KW - DISCOVERY
KW - PRINS CYCLIZATION
KW - VANILLIN
KW - POTENT ANALGESIC ACTIVITY
UR - http://www.scopus.com/inward/record.url?scp=85089725054&partnerID=8YFLogxK
U2 - 10.1007/s10593-020-02743-z
DO - 10.1007/s10593-020-02743-z
M3 - Article
AN - SCOPUS:85089725054
VL - 56
SP - 867
EP - 874
JO - Chemistry of Heterocyclic Compounds
JF - Chemistry of Heterocyclic Compounds
SN - 0009-3122
IS - 7
ER -
ID: 25093949