Standard

Synthesis of 3-Fluoropyrazolo[1,5-A]Pyridines by Fluorination of Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylates. / Alieva, Sabina V.; Vorob’ev, Aleksey Yu.

In: Chemistry of Heterocyclic Compounds, Vol. 56, No. 7, 01.07.2020, p. 957-960.

Research output: Contribution to journal › Article › peer-review

Harvard

Alieva, SV & Vorob’ev, AY 2020, 'Synthesis of 3-Fluoropyrazolo[1,5-A]Pyridines by Fluorination of Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylates', Chemistry of Heterocyclic Compounds, vol. 56, no. 7, pp. 957-960. https://doi.org/10.1007/s10593-020-02757-7

APA

Alieva, S. V., & Vorob’ev, A. Y. (2020). Synthesis of 3-Fluoropyrazolo[1,5-A]Pyridines by Fluorination of Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylates. Chemistry of Heterocyclic Compounds, 56(7), 957-960. https://doi.org/10.1007/s10593-020-02757-7

Vancouver

Alieva SV, Vorob’ev AY. Synthesis of 3-Fluoropyrazolo[1,5-A]Pyridines by Fluorination of Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylates. Chemistry of Heterocyclic Compounds. 2020 Jul 1;56(7):957-960. doi: 10.1007/s10593-020-02757-7

Author

Alieva, Sabina V. ; Vorob’ev, Aleksey Yu. / Synthesis of 3-Fluoropyrazolo[1,5-A]Pyridines by Fluorination of Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylates. In: Chemistry of Heterocyclic Compounds. 2020 ; Vol. 56, No. 7. pp. 957-960.

BibTeX

@article{e8843fdde290458a93184f502babe80d,
title = "Synthesis of 3-Fluoropyrazolo[1,5-A]Pyridines by Fluorination of Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylates",
abstract = "The reaction of methyl esters of pyrazolo[1,5-a]pyridine-2,3-dicarboxylic and 2-phenylpyrazolo[1,5-a]pyridine-3-carboxylic acids with the fluorinating reagent Selectfluor gave 3-fluoropyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester and 3-fluoro-2-phenylpyrazolo- [1,5-a]pyridine. Monitoring the progress of the reaction by 1H NMR spectroscopy showed the formation of an intermediate fluorinecontaining σ-complex.",
keywords = "electrophilic fluorination, pyrazolo[1,5-a]pyridines, Selectfluor, IBUDILAST, IMINES",
author = "Alieva, {Sabina V.} and Vorob{\textquoteright}ev, {Aleksey Yu}",
year = "2020",
month = jul,
day = "1",
doi = "10.1007/s10593-020-02757-7",
language = "English",
volume = "56",
pages = "957--960",
journal = "Chemistry of Heterocyclic Compounds",
issn = "0009-3122",
publisher = "Springer New York",
number = "7",

}

RIS

TY - JOUR

T1 - Synthesis of 3-Fluoropyrazolo[1,5-A]Pyridines by Fluorination of Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylates

AU - Alieva, Sabina V.

AU - Vorob’ev, Aleksey Yu

PY - 2020/7/1

Y1 - 2020/7/1

N2 - The reaction of methyl esters of pyrazolo[1,5-a]pyridine-2,3-dicarboxylic and 2-phenylpyrazolo[1,5-a]pyridine-3-carboxylic acids with the fluorinating reagent Selectfluor gave 3-fluoropyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester and 3-fluoro-2-phenylpyrazolo- [1,5-a]pyridine. Monitoring the progress of the reaction by 1H NMR spectroscopy showed the formation of an intermediate fluorinecontaining σ-complex.

AB - The reaction of methyl esters of pyrazolo[1,5-a]pyridine-2,3-dicarboxylic and 2-phenylpyrazolo[1,5-a]pyridine-3-carboxylic acids with the fluorinating reagent Selectfluor gave 3-fluoropyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester and 3-fluoro-2-phenylpyrazolo- [1,5-a]pyridine. Monitoring the progress of the reaction by 1H NMR spectroscopy showed the formation of an intermediate fluorinecontaining σ-complex.

KW - electrophilic fluorination

KW - pyrazolo[1,5-a]pyridines

KW - Selectfluor

KW - IBUDILAST

KW - IMINES

UR - http://www.scopus.com/inward/record.url?scp=85089751387&partnerID=8YFLogxK

U2 - 10.1007/s10593-020-02757-7

DO - 10.1007/s10593-020-02757-7

M3 - Article

AN - SCOPUS:85089751387

VL - 56

SP - 957

EP - 960

JO - Chemistry of Heterocyclic Compounds

JF - Chemistry of Heterocyclic Compounds

SN - 0009-3122

IS - 7

ER -

ID: 25290124