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Synthesis and cytotoxicity of novel cholesterol–cobalt bis(dicarbollide) conjugates. / Druzina, Anna A.; Dudarova, Nadezhda V.; Zhidkova, Olga B. et al.

In: Mendeleev Communications, Vol. 32, No. 3, 01.05.2022, p. 354-356.

Research output: Contribution to journal › Article › peer-review

Harvard

Druzina, AA, Dudarova, NV, Zhidkova, OB, Razumov, IA, Solovieva, OI, Kanygin, VV & Bregadze, VI 2022, 'Synthesis and cytotoxicity of novel cholesterol–cobalt bis(dicarbollide) conjugates', Mendeleev Communications, vol. 32, no. 3, pp. 354-356. https://doi.org/10.1016/j.mencom.2022.05.021

APA

Druzina, A. A., Dudarova, N. V., Zhidkova, O. B., Razumov, I. A., Solovieva, O. I., Kanygin, V. V., & Bregadze, V. I. (2022). Synthesis and cytotoxicity of novel cholesterol–cobalt bis(dicarbollide) conjugates. Mendeleev Communications, 32(3), 354-356. https://doi.org/10.1016/j.mencom.2022.05.021

Vancouver

Druzina AA, Dudarova NV, Zhidkova OB, Razumov IA, Solovieva OI, Kanygin VV et al. Synthesis and cytotoxicity of novel cholesterol–cobalt bis(dicarbollide) conjugates. Mendeleev Communications. 2022 May 1;32(3):354-356. doi: 10.1016/j.mencom.2022.05.021

Author

Druzina, Anna A. ; Dudarova, Nadezhda V. ; Zhidkova, Olga B. et al. / Synthesis and cytotoxicity of novel cholesterol–cobalt bis(dicarbollide) conjugates. In: Mendeleev Communications. 2022 ; Vol. 32, No. 3. pp. 354-356.

BibTeX

@article{45979321381a4bc8bb4e18cd4db0993b,
title = "Synthesis and cytotoxicity of novel cholesterol–cobalt bis(dicarbollide) conjugates",
abstract = "The novel conjugates of cholesterol with cobalt – bis(dicarbollide) were synthesized by the ring-opening reactions of the cyclic oxonium derivatives of [3,3′-Co(C2B9H11)2]– with the OH group of cholesterol 2-hydroxyethyl ether. The compounds obtained were tested for toxicity to glioblastoma U-87 MG cells and human embryo fibroblasts FECH-15 cells",
keywords = "boron cage, boron neutron capture therapy, cancer, cholesterol, cobalt bis(dicarbollide), cytotoxicity, human glioblastoma U-87 MG, lipids, liposomes",
author = "Druzina, {Anna A.} and Dudarova, {Nadezhda V.} and Zhidkova, {Olga B.} and Razumov, {Ivan A.} and Solovieva, {Olga I.} and Kanygin, {Vladimir V.} and Bregadze, {Vladimir I.}",
note = "Funding Information: The chemical studies were supported by Russian Science Foundation (grant no. 19-72-30005). The NMR spectroscopic data were obtained using the equipment of the Center for Molecular Structure Studies at the A. N. Nesmeyanov Institute of Organoelement Compounds operating with financial support from Ministry of Science and Higher Education of the Russian Federation. The biological studies were supported by the budget (project no. FWNR-2022-0023) and implemented using the equipment of the Center for Genetic Resources of Laboratory Animals at ICG SB RAS, supported by the Ministry of Education and Science of Russia (unique identifier of the project RFMEFI62119X0023). Publisher Copyright: {\textcopyright} 2022",
year = "2022",
month = may,
day = "1",
doi = "10.1016/j.mencom.2022.05.021",
language = "English",
volume = "32",
pages = "354--356",
journal = "Mendeleev Communications",
issn = "0959-9436",
publisher = "Elsevier",
number = "3",

}

RIS

TY - JOUR

T1 - Synthesis and cytotoxicity of novel cholesterol–cobalt bis(dicarbollide) conjugates

AU - Druzina, Anna A.

AU - Dudarova, Nadezhda V.

AU - Zhidkova, Olga B.

AU - Razumov, Ivan A.

AU - Solovieva, Olga I.

AU - Kanygin, Vladimir V.

AU - Bregadze, Vladimir I.

N1 - Funding Information: The chemical studies were supported by Russian Science Foundation (grant no. 19-72-30005). The NMR spectroscopic data were obtained using the equipment of the Center for Molecular Structure Studies at the A. N. Nesmeyanov Institute of Organoelement Compounds operating with financial support from Ministry of Science and Higher Education of the Russian Federation. The biological studies were supported by the budget (project no. FWNR-2022-0023) and implemented using the equipment of the Center for Genetic Resources of Laboratory Animals at ICG SB RAS, supported by the Ministry of Education and Science of Russia (unique identifier of the project RFMEFI62119X0023). Publisher Copyright: © 2022

PY - 2022/5/1

Y1 - 2022/5/1

N2 - The novel conjugates of cholesterol with cobalt – bis(dicarbollide) were synthesized by the ring-opening reactions of the cyclic oxonium derivatives of [3,3′-Co(C2B9H11)2]– with the OH group of cholesterol 2-hydroxyethyl ether. The compounds obtained were tested for toxicity to glioblastoma U-87 MG cells and human embryo fibroblasts FECH-15 cells

AB - The novel conjugates of cholesterol with cobalt – bis(dicarbollide) were synthesized by the ring-opening reactions of the cyclic oxonium derivatives of [3,3′-Co(C2B9H11)2]– with the OH group of cholesterol 2-hydroxyethyl ether. The compounds obtained were tested for toxicity to glioblastoma U-87 MG cells and human embryo fibroblasts FECH-15 cells

KW - boron cage

KW - boron neutron capture therapy

KW - cancer

KW - cholesterol

KW - cobalt bis(dicarbollide)

KW - cytotoxicity

KW - human glioblastoma U-87 MG

KW - lipids

KW - liposomes

UR - http://www.scopus.com/inward/record.url?scp=85131375387&partnerID=8YFLogxK

U2 - 10.1016/j.mencom.2022.05.021

DO - 10.1016/j.mencom.2022.05.021

M3 - Article

AN - SCOPUS:85131375387

VL - 32

SP - 354

EP - 356

JO - Mendeleev Communications

JF - Mendeleev Communications

SN - 0959-9436

IS - 3

ER -

ID: 36436129